摘要
[目的]观察无花果叶提取物体外抗单纯疱疹病毒-1型的作用。[方法]采用原代兔肾细胞培养技术,以无环鸟苷为阳性对照,通过观察细胞病变检测无花果叶水体物、醇提物对病毒的直接作用、治疗作用和预防作用。[结果]无花果叶水提物、醇提物的半数毒性浓度(TC50)分别为184.4 mg/ml和485.3 mg/ml。无花果叶提取物体外对HSV-1具有明显的抑制和杀灭作用。[结论]无花果叶提取物体外具有明显的抗HSV-1的作用。
[Objective]The antiviral effect of the fig leave extract on herpes simplex type-1 virus is studied in this paper. [Methods]The experiment is conducted with the rabbit kidney cells in vitro. The cytopathic effects are observed as indicator of the antiviral effect of the fig leaf extract and ACV as positive drug control, [Results]485.3 mg/ml TC50 of the fig leaf alcohol extract and 184.4 mg/ml fig leaf water extract have been sampled. The results show that the fig leaf extract can inhibit and kill virus in vitro. [Conclusion]Its effect on herpes simplex type-1 virus in vitro is positively concluded.
出处
《预防医学论坛》
2009年第5期394-395,399,共3页
Preventive Medicine Tribune
基金
山东省济宁市科技局资助课题
