摘要
为了解儿科住院患儿的肾功能受损情况，本文检测了179例儿科常见病住院患儿的尿NAG、r-GT、Cre，并与30例健康儿童进行对照。结果显示，各疾病组患儿尿NAG、r-GT均比健康儿童升高。用酶活性与尿肌酐比值NAG／Cr（U／g．Cr）、r-GT／Cr（U／g．Cr）表示酶活性时，所有患儿尿NAG均显著高于正常对照组，尿r-GT高于正常组仅见于神经、呼吸、血液系统疾病及急性肠炎组患儿，这表明NAG在反映肾功能受损方面比r-GT敏感。作者以为，患各种疾病时，都或多或少有肾功能受损，建议对住院及门诊患儿常规进行简单、易行、无损伤的尿NAG检查，以监测肾功能变化。
For understanding the kidney function of the inpatients in Pediatric Department, urine NAcetylβ-D-Glucosminidase (NAG), r-Glutamyl transpeptidase (r-GT) and Creatinine (cre) of 179 common podiatric disease cases were detected in this essay, and compared with 30 healthy children. The urine NAG & r-GT in all the disease groups were higher than those in normol comparable group. The enzyme activity was expressed as the ratio of urine NAG to Cre (Unit: U/g. cr) and the ratio of urine r-GT to Cre (Unit: U/g. ct). The former (NAG) was higher in all kinds of disease in children than in normal comparable group, there were high remarkable. The latter (r-GT) was higher in nervous, respiratory, blood system diseases and in acute enteritis patients.This results that as the indicator of the renal function NAG were more sensitive than r-GT. The author indicatedthat renal injury would happened in all kinds of diseases and suggested that urine NAG estimation should provide a simple, cheap and harmless way of inspecting renal function for inpatients and outpatients.
出处
《福建医药杂志》
CAS
1998年第2期12-14,共3页
Fujian Medical Journal
关键词
NAG
r-GT
CRE
检测
尿
肾功能
Urine NAG Urine r-GT Urine ore Detection Clinical significance
