摘要
本实验采用绞股蓝总皂甙（ＧＰｓ）治疗小鼠血吸虫病，观察其对血吸虫性肝纤维化的影响。结果表明：ＧＰｓ治疗组肝虫卵肉芽肿反应增长比和肝纤维化程度均明显小于感染对照组（Ｐ＜０．０５）。提示ＧＰｓ具有减轻血吸虫性肝纤维化的作用。
The article reports the inhibitive effect of gypenosides(GPs) on liver fiberosis of Schistosoma japonicum infected mice.In Gps treated group,the granuloma reaction and the level of liver fiberosis were less than that of control group(P<0.05).The results suggested:(1)Gps could decrease liver fiberosis of schistosoma japonicum infected mice;(2)Free radicals played an important role in granulom formation and improvement.
