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住院患者HBV感染状况及手术史与HBV感染的关系

Status of Hepatitis B Virus Infection and Relationship Between Operation History and HBV Infection in Inpatients
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摘要 目的探讨医院住院患者HBV感染状况及手术史与HBV感染的关系。方法选择于本院住院患者389例,其中有手术史患者167例,无手术史患者222例。以ELISA方法检测乙肝两对半,将两组出现的11种模式的阳性率进行比较。结果389例住院患者的HBsAg阳性率为13.88%,HBV感染率为58.09%,HBV免疫学指标阴性率41.91%。其中HBsAg、HBeAb、HBcAb阳性者38例(9.76%),HBcAb阳性者25例(6.43%),HBsAg、HBcAb阳性者13例(3.34%)。两组间比较显示,有手术史的患者HBV感染率显著高于无手术史患者(P<0.01)。且两组间,HBsAg、HBeAb、HBcAb阳性模式和HBcAb阳性模式的比较显示有手术史的患者HBV感染阳性率显著高于无手术史患者(P<0.001)。结论住院患者是HBV高感染危险人群。手术是导致医院内HBV感染的方式,需要采取预防措施。 Objective To investigate the status of hepatitis B virus infection and the correlation between the operation history and HBV infection in inpatients. Methods Totally 389 inpatients were selected from Wuhan Municipal Hospital of Traditional Chinese Medicine, among them, 167 patients with operation history and 222 patients without operation history. Half and two pairs of HBV immunology indicators were detected in two groups; 11 models were separated and determined ac- cording to HBV immunology indicators. The differences of HBV infection rates were compared between the two groups. Results Among 389 inpatients, HBsAg positive rate was 13.88 %, HBV infected rate was .58.09 %, and HBV negative rate was 41.91%. There were 38 positive cases with HBsAg, HBeAb, HbcAb (9.76 % ), 25 .positive cases with HbcAb (6.43 % ), and 13 positive cases with HBsAg, HbcAb (3.34%). HBV infection rate of inpatients with operation history was significantly higher than that of inpatients without operation history (P〈 0.01 ). Comparison of positive models HBsAg, HbeAb, HbcAb and negative model HbcAb showed that the positive rate of HBV infection of inpatients with operation history was significantly high- er than that of inpatients without operation history ( P 〈 0. 001 ). Conclusions Inpatients are the high - risk population of HBV infection. Operations bring about HBV infection in the hospitals, so it is necessary to take protection measures.
作者 禹红 吕继富
出处 《实用预防医学》 CAS 2009年第3期712-714,共3页 Practical Preventive Medicine
关键词 乙型肝炎病毒 医院感染 免疫学指标 手术 住院患者 Hepatitis B virus Nosocomial infection Immunology indicator Operation Inpatient
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