摘要
[目的]探讨肢体恶性骨肿瘤的微波高温原位灭活保肢术的临床效果。[方法]将荷瘤骨段与正常组织分离后原位热灭活,经过灭活骨段的加固措施,使其能够承重,且保留了临近的自然关节。[结果]经本术式治疗的309例肢体肿瘤结果:3年以上存活率为60.2%,对多数病人而言,保留了功能甚为满意的肢体,近期并发症及远期并发症均较文献报告低。[结论]原位灭活保肢术是一种可靠、有效和简化的术式,肿瘤学和功能学效果均令人鼓舞。
[ Objective] To analyze the clinical effect of microwave hyperthermia in limb salvage surgery for malignant bone tumor of extremities. [Methods] From July 1999 to July of 2005, 309 patients with malignant or bone tumors of extremities were treated by heat necrosis of tumor - bearing bone in situ for limb salvage. The most common diagnosis was osteosarcoma. The first step of the traditional limb salvage was en bloc resection of the tumor - bearing bone. For the novel method, the tumor bearing bone was just separated from surrounding normal tissues, and was devitalized by hyperthermia in situ. After re - strengthening the dead bone, its mechanical property became strong enough to support the body weight. [Results] The beyond 3 years survival rate was 60. 2% for high - grade malignancy. In great majority of the patients, cosmetic and useful limbs were preserved. The complication rate was lower than that in the literature reports. [ Conclusion] The long term experience has proved that the new method has made its way in the field of orthopedic oncology. The applying of hyperthermia for treatment of bone tumors is an effective, simple, and inexpensive method. The oncological and functional results are encouraging. Hyperthermia should deserve more attention than it has in the clinical practice.
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2009年第11期801-806,共6页
Orthopedic Journal of China
关键词
恶性骨肿瘤
微波
高温
保肢术
malignant bone tumors
microwave
hyperthermia
limb salvage
