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复方磷酸可待因口服溶液治疗小儿急性呼吸道感染疗效观察 被引量:1

The Effect of Compound Codeine Phosphate Solution in Treating Children with Acute Respiratory Tract Infection
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摘要 目的:评估复方磷酸可待因口服溶液对小儿呼吸道感染的的止咳、化痰、祛痰效果。方法:将2007年1~12月间确诊为急性呼吸道感染伴有咳嗽、咳痰症状的2岁以上小儿180例,随机分为观察组90例,对照组90例,比较复方磷酸可待因口服液、复方桔梗氯化铵口服液两种药物起效时间、镇咳持续时间、临床症状总有效率。结果:复方磷酸可待因口服溶液起效时间(0.56±0.22)h,短于对照组,持续时间(4.18±1.76)h,长于对照组,P均<0.01。临床症状总有效率(咳嗽90.0%,痰量及粘稠度71.1%)均明显优于对照组(P均<0.01)。结论:复方磷酸可待因口服溶液是适于2岁以上呼吸道感染患儿的快速祛痰止咳药品,镇咳效果好,镇咳作用持续时间长。 Objective: To evaluate the effect of compound codeine phosphate solution in treating children with acute respiratory tract infection. Methods: One hundred and eighty children, more than two years old, with acute respiratory tract infection with symptoms of cough and phlegm were divided into two groups: observation group and control group in 2007. The therapeutic effect and effective rate of both groups were observed and compared. Results: The effect of compound codeine phosphate solution started earlier (0.56 ± 0.22 h) and its duration lasted longer (4.18 ±1.76 h) compared with those of the control group (P 〈 0.01 ). The improving-rate of clinical symptoms (90.0% in cough and 71.1% in phlegm) were better than those in the control group (P 〈 0.01 ). Conclusions: Compound codeine phosphate solution is suitable for children elder than two years and with acute respiratory tract infection. It has a good and quick effect in treating and relieving cough and phlegm in children.
机构地区 上海市江湾医院
出处 《儿科药学杂志》 CAS 2009年第3期30-32,共3页 Journal of Pediatric Pharmacy
关键词 呼吸道感染 复方磷酸可待因口服溶液 小儿 Respiratory tract infections Compound codeine phosphate solution Children
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  • 1Houtmeyers E, Gosselink R, Gayan-Ramirez G, et al. Effects of drugs on mucus clearance [J]. Eur Respir, 1999, 14: 452-467.
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