摘要
目的:探讨不同发作类型等因素对癫痫患者发生抑郁和生活质量的影响。方法:采用汉密尔顿抑郁量表和抑郁自评量表评价患者的抑郁状况,采用QOLIE-31量表评定患者生活质量。采用PSSS量表评估患者的社会支持情况。结果:癫痫患者抑郁发生率比普通人群高,其中GTCS发作组和复杂部分性发作组抑郁发生率最高,首次发病年龄小的患者抑郁发生率高,差异有统计学意义(P<0.01);癫痫患者的生活质量较正常人为低,GTCS发作组和复杂部分性发作组最低,差异明显(P<0.01);起病年龄对生活质量有影响。结论:起病早,GTCS发作和复杂部分性发作者,情感状态受损明显,生活质量水平相对较差。对患者生活质量影响最明显的因素依次为抑郁、发作类型、起病年龄和社会支持。
Objective： To explore probable influencing factors of depression and quality in life of patients with epilepsy of the different seizures. Methods ： The depression situation of 165 patients were scored with Hamilton depression scale （HAMD） and the perceived social support scale （PSSS）. Their quality of life were also assessed with Quality Of Life In Epilepsy 31 （ QOLIE-31 ）. Results ： The situation of depression of patients with epilepsy were worse than that of the common people, and the scores of patients with general- ized tonie-elonic seizure or complex partial seizure were the worst. The more early the first seizure was, the worse were the depression situations of patients with epilepsy. The quality of life of patients was similar to the situation of depression. The patients of simple partial seizure got the most social support, while muscle clonic seizure kept the least. The more early the first seizure was, the worse were the psychological situations with the lower quality of life. Conclusion： The situation of depression of patients with epilepsy were influ- enced by the categories of seizures and the time of the first seizure. The quality of life of patients with epilepsy were influenced by the categories of seizures and the time of the first seizure. The influencing factors of quality of life were depression, type of seizure, age of first onset and social support in turn.
出处
《江苏大学学报（医学版）》
CAS
2009年第3期243-246,共4页
Journal of Jiangsu University：Medicine Edition
关键词
癫痫
抑郁
生活质量
影响因素
发作类型
epilepsy
depression
quality of life
influencing factor
seizure types
