摘要
脐尿管癌临床少见，预后不良，发病机理一般认为是脐尿管的移行上皮化生所致。临床表现主要是无痛性肉眼血尿，伴尿频尿急，尿中含有粘液及耻骨上肿块。通过ＣＴ、Ｂ超和膀胱镜等多项检查再根据脐尿管癌的诊断标准，１１例中有７例患者术前作出正确诊断。２例有盆腔淋巴结转移，其中１例合并腹腔广泛转移。治疗以手术为主，采用扩大的膀胱切除术，即包括膀胱顶部、腹横筋膜和部分腹膜连同肿瘤整块切除，病理报告均为脐尿管粘液性腺癌。术后生存３例，２例术后１年，１例术后６年。５年存活率为９％。
Eleven cases of urachus adenocarcinoma were reported. This kind of tumor is rare clinically and the prognosis is poor. Metaplasia of transitional epithelial cells is believed to be the etiologic mechanism of this disease. Painless gross hematuria, urgency and frequency of urination, mucus in urine and suprapubic mass were the common clinical manifestations in these patients.Preoperative diagnosis of urachus cancer was made in 7 cases by means of CT, Bultrasonic and cystoscopic examination. Pelvic lymph node metastasis was found in 2 cases and one of them had diffuse peritoneal involvement. Extended cystectomy including excision of fundus of the bladder, transversalis fascia, part of peritoneum and the tumor is the desirable treatment. The diagnosis of urachus adenocarcinoma was confirmed pathologically in all the 11 cases. Three patients are alive after operation,2 for one year, and one case for 6 years.The 5year survival rate of this series is 9%.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1998年第5期343-345,共3页
Chinese Journal of Clinical Oncology
