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慢性胃炎状态下跨膜电位改变

TRANSMUCOSAL POTENTIAL DIFFERENCE IN CHRONIC GASTRITIS
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摘要 观察了慢性胃炎状态下跨胃粘膜电位(GTPD)的变化以及与此相关的某些因素,发现GTPD的下降与粘膜腺体萎缩、肠化、活动性炎症等粘膜病变程度一致。幽门弯曲菌感染、胆汁反流、脂质过氧化、粘液产量下降等是导致GTPD降低的部分因素。 Transmucosal potential difference (GTPD) was measured endoscopically in 90 cases of patients with chronic gastritis.GTPD values varied in different regions,being highest in greater curvature and lowest in lesser curvature.The degree of decrease of GTPD was consistent with the degree of muco-sal lesions.Atrophic change,intestinal metaplasia and active inflammation showed a marked decline in GTPD.C.pylori infection caused further decrease of the antral GTPD.GTPD in antrum was correla- ted positively with the gastric mucous production and inversely with the levels of bile regurgitation and lipid peroxide.It is concluded that chronic mucosal lesions,C.pylori infection,regurgitation of bile into the stomach aqd lipid peroxidation are responsible to the reduction of GTPD in chronic gastritis.
出处 《解放军医学杂志》 CAS CSCD 北大核心 1990年第5期349-352,共4页 Medical Journal of Chinese People's Liberation Army
关键词 胃炎 跨粘膜电位 胃粘膜屏障 Gastric transmucosal potential difference Gastric mucosal barrier Chronic gastritis
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参考文献3

  • 1钟福孙,胡文尧,冯驰.硫代巴比土酸比色法测定血清过氧化脂质[J]临床检验杂志,1986(03).
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