摘要
目的观察右旋酮洛芬氨丁三醇在治疗带状疱疹神经痛中的疗效和安全性。方法将入选的132例带状疱疹患者随机分为试验组(71例)和对照组(61例),试验组口服阿昔洛韦0.2g,5次/d,右旋酮洛芬氨丁三醇25mg,3次/d;对照组口服阿昔洛韦0.2g,5次/d,布洛芬0.3g,3次/d,分别在治疗第3、5和7天时观察疗效及其不良反应。结果右旋酮洛芬氨丁三醇联合阿昔洛韦能明显改善患者的疼痛症状,两组有效率比较,差异无显著性意义(P>0.05)。试验组不良反应发生率为7.46%,对照组为20.33%,两者差异有显著性意义(P<0.05)。结论右旋酮洛芬氨丁三醇联合阿昔洛韦治疗。能有效缓解带状疱疹神经痛,且不良反应率低。
Objective To evaluate the clinical efficacy and safety of patients with herpes zoster pain syndrome in the treatment with dexketoprofen trometamol. Methods The patients were divided into test and control group. The test group was treated with dexketoprofen trometamol and aeyelovir, and the control group was treated with ibuprofen and aeyclovir . The effieience and side effect were evaluated in the day of 3,5,7. Results The symptom of herpes zoster pain were improved in both groups, there were no significant difference in efficacy between them（ P 〉 0.05 ）. But The incidence of adverse reactions of test and control group were 7.4-6% and 20.33 % respectively. They had singnifieant difference （P 〈0. 05）. Conclusions Combination of dexketoprofen trometamol and ibuprofen showed a good clinical efficacy in relief of herpes zoster pain syndrome and lower incidence of adverse reactions in the treatment of herpes zoster, and therefore deserves further clinical applications.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2009年第6期355-356,共2页
The Chinese Journal of Dermatovenereology
