摘要
本文在鞠躬和Swanson有关大鼠终纹床核细胞构筑学研究的基础上,用ABC或PAP免疫组化结合葡萄糖氧化酶-DAB-硫酸镍铵呈色法,对大鼠终纹床核内5-HT免疫阳性神经纤维和终支(简称5-HT纤维)的分布进行了研究。结果如下:终纹床核内的5-HT纤维由较粗纤维、细纤维和膨体型纤维组成。除卵圆形核、囊旁核、梭形核、后背核和主核含3种纤维及终纹床核纹延部仅有膨体型纤维外,终纹床核其余区域中5-HT纤维为细纤维和膨体型纤维的混合。在前部,以其腹内侧部尾侧的5-HT纤维密度最高,腹外侧部及背内侧部次之,背外侧部吻侧最低;在后部,则以腹外侧部密度最高,背外侧部次之,内侧部最低。上述结果表明,终纹床核内各区间5-HT纤维的分布密度和纤维特征的差别基本上与终纹床核各区的个体发生顺序吻合。此外,本文还讨论了终纹床枝内5-HT纤维与5-HT受体不匹配现象。
Based upon Ju and Swanson's studies on the eytoarchitecture of the bed nuclei of stria terminalis (BST) of the rat, the present work studies in detail the distribution of serotonin-immunoreactive fibers and terminals (5-HT-ir fibers) in the BST of the rat with ABC or PAP technique visualized with glucose oxidase-DAB-nickel method. The results are as followsithree types of 5-HT-ir fibers were identified in the BST, viz. thick fibers, thin fibers and varicose fibers. Only varicose fibers were found in the stria extension of the BST, whereas the rest of the BST contained other types as well. In the oval nucleus, juxitacapsular nucleus, fusiform nucleus, posterior dorsal nucleus and principle nucleus,all three types of 5-HT-ir fibers were observed, while the remaining parts of the BST were occupied with thin and varicose fibers. These fibers were distributed unevenly in the BST, with highest density in the ventromedial part of the anterior ventral area and the ventrolateral part of the posterior division; moderate density in the anterior dorsal area, the ventrolateral part of the anterior ventral area and the dorsolateral part of the posterior division; and were scattered in the anterior lateral area and the medial part of the posterior division. The difference in density of 5-HT-ir fibers among various areas of the BST corresponds generally with the sequence of ontogenesis of the BST. Mismatch of the distribution of 5-HT-ir fibers and 5-HT receptors in the BST of the rat is also discussed.
出处
《解剖学报》
CAS
CSCD
北大核心
1990年第2期160-165,共6页
Acta Anatomica Sinica
基金
国家自然科学基金
关键词
终纹床核
5-羟色胺
免疫组化
Bed nuclei of stria terminalis (BST)
5-HT
Immunohistochemistry
Rat
