期刊文献+

TLRs的负性调节因子 被引量:6

下载PDF
导出
摘要 20世纪90年代.美国著名的免疫学家Janeway提出了关于固有免疫系统病原体的模式识别理论。该理论认为。微生物病原体及其产物共有某些非特异性高度保守的分子结构,如脂多糖(LPS),
出处 《天津医科大学学报》 2009年第2期331-334,338,共5页 Journal of Tianjin Medical University
基金 国家自然科学基金资助项目(30770432 30870562) 浙江省自然科学发展基金面上项目(Y205509) 天津市应用基础及前沿技术研究计划项目(08JCYBJC07700) 教育部科学技术研究重点项目(206007) 天津市高等学校科技发展基金项目(20050109)
  • 相关文献

参考文献22

二级参考文献92

  • 1HAMPTON R Y,GOLENBOCK D T,PENMAN M,et al.Recognition and plasma clearance of endotoxin by scavenger receptors[J].Nature,1991,352(6333):342-344.
  • 2HAWORTH R,PLATT N,KESHAV S,et al.The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock[J].J Exp Med,1997,186(9):1431-1439.
  • 3SUZUKI H,KURIHARA Y,TAKEYA M,et al.A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection[J].Nature,1997,386(6622):292-296.
  • 4GANTNER B N,SIMMONS R M,CANAVERA S J,et al.Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor2[J].JExpMed,2003,197(9):1107-1117.
  • 5HOEBE K,GEORGEL P,RUTSCHMANN S,et al.CD36 is a sensor of diacylglycerides[J].Nature,2005,433 (7025):523-527.
  • 6CHOW J C,YOUNG D W,GOLENBOCK D T,et al.Toll-like receptor-4 mediates lipopolysaceharide-induced signal transduction[J].J Biol Chem,1999,274(16):10689-10692.
  • 7ZHANG G,GHOSH S.Negative regulation of toll-like receptor-mediated signaling by Tollip[J].J Biol Chem,2002,277(9):7059-7065.
  • 8NOMURA F,AKASHI S,SAKAO Y,et al.Cutting edge:endαtoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression[J].J Immunol,2000,164(7):3476-3479.
  • 9MATSUGUCHI T,MUSIKACHAROEN T,OGAWA T,et al.Gene expressions of Toll-like receptor 2,but not Toll-like receptor 4,is induced by LPS and inflammatory cytokines in mouse macrophages[J].J Immunol,2000,165(10):5767-5772.
  • 10YEO S J,YOON J G,HONG S C,et al.CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide:alterations in IL-1 receptor-associated kinase expression[J].J Immunol,2003,170 (2):1052-1061.

共引文献40

同被引文献102

引证文献6

二级引证文献25

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部