摘要
脂蛋白脂酶（LPL）是富含甘油三酯脂蛋白代谢的关键酶，其基因突变影响LPL活性，造成甘油三酯（TG）水平升高和高密度脂蛋白（HDL）水平降低，导致脂代谢紊乱，与冠心病、肥胖高血压、2型糖尿病及慢性肾脏疾病有一定的相关性，但就目前的研究看来，结果存在差异，一些问题还需进一步阐明。
Lipoprotein Lipase （LPL） is a key enzyme of lipoprotein metabolism. Its gene mutant influences LPL＇ s activity and increase triglyceride （TG） level while lowering high - density lipoprotein （HDL） level, which resuits in lipid metabolic disorder. These are considered to contribute to some diseases like coronary atherosclerotic heart disease, obesity - related hypertension and type2 diabetes and chronic kidney disease. But research results differ at present and a number of issues are left to be further clarified.
出处
《中国临床新医学》
2009年第5期531-533,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
脂蛋白脂酶
冠心病
肥胖高血压
2型糖尿病
慢性肾脏疾病
Lipoprotein Lipase
Coronary atherosclerotic heart disease
Obesity- related hypertension
Type2 diabetes
Chronic kidney disease
