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新辅助化疗治疗晚期卵巢癌的临床研究 被引量:3

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摘要 目的:探讨新辅助化疗(NACT)在晚期期卵巢癌辅助治疗中的临床效果。方法:37例卵巢癌患者,术前采用1~3个疗程的静脉化疗,之后全部行卵巢癌根治术。通过观察患者疗效评定、化疗毒副反应、手术时间、减少术中出血、减少手术残留、有效减少手术并发症等,评价新辅助化疗在卵巢癌治疗中的作用及安全性。结果:化疗总有效率为83.8%(31/37),胸、腹水控制有效率为91.3%(21/23),患者一般情况改善,化疗前后Karnofsky评定均有明显提高。化疗毒副反应轻微。所有患者化疗后均进行了广泛性全子宫、双附件、大网膜、阑尾及受累脏器切除术和淋巴清扫术。结论:卵巢癌新辅助化疗是安全有效的,毒副作用轻微。新辅助化疗(化疗+手术+化疗)提高手术成功率,延长生存期,对晚期卵巢癌具有较重要的价值,值得推广应用。
出处 《中国社区医师(医学专业)》 2009年第10期78-79,共2页
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参考文献4

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