摘要
利用多种色谱技术进行分离纯化,根据其理化性质和光谱分析鉴定结构,研究黄皮(Clausena lansium)的化学成分。从黄皮茎提取物二氯甲烷部分分离得到10个化合物,分别鉴定为imperatorin (1),8-hydroxyfurocoumarin(2),5-hydroxy-8-(3'-methyl-2'-butenyl)furocoumarin(3),indizoline(4),methylcarbazole-3-carboxylate(5),3-formylcarbazole(6),clausine-O(7),clauszoline-K(8),1-(3'-methyl-2'-butenyl)-2-hydroxy-3-formylcarbazole(9)和β-谷甾醇(10)。其中,化合物(1)、(7)、(8)、(9)首次从黄皮中分离得到。
This paper studies the composition of Clausena Lansium. Several chromatographic methods （including silica gel, sephadex LH-20, preparative TLC and HPLC） were applied in the isolation procedure, the structures were determined by NMR and EI-MS. Ten compounds were obtained, and identified as imperatorin （1）, 8- hydroxyfurocoumarin （2）, 5-hydroxy-8-（3′-methyl-2′-butenyl） furocoumarin （3）, indizoline （4）, methyl carbazole-3-carboxylate （5）, 3-formylcarbazole （6）, clausine-O （7）, clauszoline-K （8）, 1-（3′- methyl-2′-butenyl）- 2-hydroxy-3-formylcarbazole （9）, β-sitosterol （10）respectively. Compounds （1）, （7）, （8） and （9） were isolated from the species of Clausena Lansium for the first time.
出处
《科技导报》
CAS
CSCD
北大核心
2009年第10期82-84,共3页
Science & Technology Review
关键词
黄皮
化学成分
咔唑生物碱
呋喃香豆素
Clausena lansium
chemical constituent
carbazole alkaloid
furocoumarin
