摘要
目的分析医院泌尿道感染病原菌的分布及耐药情况,为临床合理选用抗菌药物提供依据。方法采用ATB系统和纸片扩散法对中段尿标本培养分离的病原菌进行鉴定和药敏试验,WHONET5.3软件分析病原菌的分布及耐药情况。结果大肠埃希菌是泌尿道感染最主要的致病菌(57.6%),其次为肠球菌属(14.4%);药敏结果显示,肠杆菌科细菌及鲍氏不动杆菌对亚胺培南的敏感性为100.0%,铜绿假单胞菌有13.6%的耐药率,革兰阳性球菌对糖肽类抗菌药物及利奈唑烷最为敏感。结论临床医师应关注泌尿道感染致病菌的种类及对临床常用抗菌药物的敏感情况,以合理选用抗菌药物。
OBJECTIVE To investigate the distribution and antibiotic susceptibility of pathogens causing urinary infection, for the guide of rational use of antimierobial agents in clinic. METHODS The bacteria isolated from the middle segment urine sample were identified by ATB system, and K-B method was used to study the antimicrobial resistance. The data were analyzed by WHONET 5.3. RESULTS Escherichia coli was one of the most common bacteria in the urinary tract infection （57.6%）, and then were Enterococcus （14.4%）. The results of antibiotic susceptibility test in vitro showed the susceptibility rate of Enterobacteriaeeae and Acinetobacter baumannii to imipenem, was 100.0%, hut the resistance rate of Pseudomonas aeruginosa was 13.6%. Gram-positive cocci were sensitive to glyeopeptide antibiotics and linezolid. CONCLUSIONS Clinician should pay attention to the kinds of pathogenic bacteria causing urinary tract infection and their susceptibility to clinically common used antibiotics for reasonable use of drugs.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第11期1447-1449,共3页
Chinese Journal of Nosocomiology
关键词
泌尿道感染
病原菌
耐药性
Urinary tract infection
Pathogen
Resistance
