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轻度肺通气功能障碍对单肺通气期间氧合和肺内分流的影响 被引量：7

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摘要 目的:观察术前轻度肺通气功能障碍对单肺通气期间血液氧合及肺内分流的影响。方法:40例ASAⅠ～Ⅱ级择期需行单肺通气开胸手术的成年患者,根据术前肺功能测定结果,将患者分为肺通气功能正常组(Ⅰ组)及轻度肺通气功能障碍组(Ⅱ组),每组20例。分别于患者右侧卧双肺通气10min(T0),单肺通气10min(T1)、20min(T2)、30min(T3)、40min(T4)抽取动、静脉血行血气分析并计算肺内分流率(Qs/Qt)。结果:Ⅰ组患者单肺通气各时点动脉血氧分压(PaO2)较双肺通气时明显下降(P<0.05),Qs/Qt明显增加(P<0.05)。Ⅱ组患者单肺通气各时点PaO2较双肺通气时明显升高(P<0.05),Qs/Qt则无明显改变,两组患者动脉血二氧化碳分压(PaCO2)、pH值、平均动脉压(MAP)、心率(HR)、脉搏血氧饱和度(SpO2)、呼气末二氧化碳分压(PETCO2)等在单肺通气期间无明显改变(P>0.05);与Ⅰ组比较,Ⅱ组患者各时点PaO2、Qs/Qt均有明显差异(P<0.05),而PaCO2、pH、MAP、HR、SpO2、PETCO2等则无明显差异(P>0.05)。结论:术前轻度肺通气功能障碍患者较肺通气功能正常者单肺通气期间具有更好的血液氧合趋势,肺内分流则无明显增加,单肺通气期间低氧血症发生的危险性降低。
作者 代冬梅 温海明 李红新 陈树明 詹锦六
机构地区 广州市胸科医院麻醉科
出处 《实用医学杂志》 CAS 北大核心 2009年第11期1825-1827,共3页 The Journal of Practical Medicine
基金 广州市医药卫生科技一般引导项目(编号:2007-YB-093)
关键词 肺通气 肺功能试验 氧合 肺内分流
分类号 R614 [医药卫生—麻醉学]
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参考文献10

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共引文献60

同被引文献51

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引证文献7

二级引证文献17

实用医学杂志
2009年 第11期

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