摘要
目的分析系统性红斑狼疮（ＳＬＥ）患者的死因，目的在降低其病死率。方法对４６５例ＳＬＥ患者中的９０例死者死因进行分析。结果最主要死因是ＳＬＥ本身４０例（４４４４％），其次是感染３０例（３３３３％），心血管疾病１２例（１３３３％）。ＳＬＥ与感染致死较常发生于年轻患者。ＳＬＥ死亡多发生在诊断后的头三年。结论ＳＬＥ死亡最主要原因是ＳＬＥ本身，故对ＳＬＥ活动应积极治疗，但不能过度，以免引发感染而死亡。
bjective To analyse the causes of death in a cohort of patients with systemic lupus erythematosus (SLE) and to decrease the mortality of SLE. Methods 90 patients died in a cohort of 465 patients with SLE were analysed. Results SLE itself was the most common cause of death occurring in 40 patients (4444%), followed by infection (n=30, 3333%), cardiovascular disease (n=12,1333%). Deaths due to SLE and infection were more common among younger patients. The risk of death due to SLE was greatest within the first 3 years after diagnosis. Conclusion The most common death cause of SLE is SLE itself, so it should be treated positively, but excessive medication must be avoided, otherwise infection would occur, leading to a increase of the mortality.
出处
《中华肾脏病杂志》
CAS
CSCD
北大核心
1998年第2期114-116,共3页
Chinese Journal of Nephrology
