摘要
目的研究空腹血糖水平与中老年冠状动脉粥样硬化性心脏病(冠心病)患者冠状动脉病变狭窄程度及病变支数的相关性。方法冠状动脉造影确诊冠心病221例,其中单支病变组67例,多支病变组154例,对冠状动脉造影结果采用Gensini积分系统定量评定冠状动脉血管病变狭窄严重程度,以冠状动脉造影正常者(36例)为对照组,分析空腹血糖与冠状动脉病变狭窄程度、病变支数的相关性。结果多支病变组与对照组比较空腹血糖水平差异有显著性(P<0.05),中老年冠心病患者冠状动脉病变Gensini积分及冠状动脉病变支数与空腹血糖水平均呈正相关(相关系数分别为r=0.32,P<0.01;r=0.284,P<0.05)。结论空腹血糖水平与中老年冠心病患者冠状动脉病变狭窄程度及病变支数密切相关,严格控制空腹血糖有助于中老年冠心病的有效防治。
[Objective] To investigate the relationship between fasting plasma glucose (FPG) and the severity of stenosis and number of stenosis in elderly patients with coronary heart disease (CHD). [Methods] 221 patients diagnosed as CHD by coronary angiography, 67 patients with single ramus and 154 patients with multitude ramus were enrolled in the study. The severity scale of coronary artery stenosis was quantitatively assessed according to coronary angiography by Gensini score. There were 36 normal subjects who underwent coronary angiography and not proved to be CHD (control group). The eorrelation between FPG and the severity of stenosis and number of stenosis in elderly patients with CHD was analyzed. [Results] There were significant differences in FPG among patients of multitude ramus group and that of control group (P 〈0.05). The Gensini score of CHD stenosis and the number of stenosis coronary artery were correlated positively with FPG (r =0.32, P 〈0.01; r =0.284, P 〈0.05). [Conclusion] The FPG is closely related to the severity of stenosis and number of stenosis in elderly patients with CHD, a better control of FPG will be helpful to prevent and care in elderly CHD patients.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2009年第10期1522-1525,共4页
China Journal of Modern Medicine