摘要
目的:探讨幽门螺杆菌(Hp)感染与缺铁性贫血(IDA)的关系以及根除治疗的意义。方法:确诊IDA合并Hp感染患儿56例,随机分为治疗组(28例)和对照组(28例),分别进行铁剂治疗加抗Hp感染治疗和单纯的铁剂治疗,分析开始治疗6周后、随访1年后的疗效。结果:开始治疗6周后,根除治疗组患儿的血清铁蛋白(SF)水平为(38.14±18.43)g/L,显著高于对照组患儿(P<0.05);随访1年,原根除治疗组患儿SF水平达到(39.18±15.92)g/L,显著高于原对照组患儿的(22.13±12.94)g/L,Hb、MCV、MCH三项指标也显著高于对照组,差异有统计学意义(P<0.01,P<0.05);治疗过程中均未发现严重副作用。结论:Hp感染与IDA关系密切,根除Hp感染可明显提高IDA的疗效,对Hp阳性的IDA患儿应同时Hp根除治疗。
Objective： To investigate the relationship between Helicobacter pylori（Hp） infection and iron deficiency anemia （IDA） and the significance of radical treatment. Methods： Confirmed 56 cases of children with IDA merge Hp infection, were randomly divided into treatment group（28 cases） and control group（28 cases）, respectively to iron therapy plus anti-Hp infection treatment and simple iron treatment, analyzed the efficacy of the fifth week to begin treatment and the first year follow-up. Results： In the fifth week to begin treatment, the radical treatment group of children with serum ferritin （SF） level was （38.14± 18.43） g/L,significantly higher than those children in control group （P〈0.05）,with 1 year follow-up, the SF levels of the radical treatment group children was （39.18±15.92） g/L, significantly higher than the control group （22.13± 12.94） g/L, the three indicators of Hb, MCV, MCH were significantly higher, the difference had statistical significance （P〈 0.01 or P〈0.05） and the treatment process were not found serious side effects. Conclusion： There is close relationship between Hp infection and IDA, clinical treatment to children with IDA merge Hp infection should be given iron treatment and radical treatment of Hp infection.
出处
《中国医药导报》
CAS
2009年第18期35-36,共2页
China Medical Herald
关键词
缺铁性贫血
幽门螺杆菌感染
根除
Iron deficiency anemia
Helicobacter pylori infection
Radical treatment
