摘要
目的分析非手术方法治疗眼睑痉挛和面肌痉挛的效果。方法统计150例眼睑及面肌痉挛患者。将痉挛时间低于6个月的50例患者分为两组，一组采取局部冰敷的方法治疗（25例），另一组不做任何处理（25例）；对100例痉挛时间大于6个月的患者应用A型肉毒素局部注射治疗。结果25例患者冰敷1—2周后，其中23例症状完全消失，2例痉挛减轻：25例不做处理的．15例于1～2个月后症状自行消失．7例痉挛减轻，3例发展为持续性眼睑痉挛；痉挛时间大于6个月的100例患者A型肉毒素局部注射后，98例患者症状完全缓解或明显缓解．2例患者治疗无效。所有注射A型肉毒素的患者均未出现全身毒副作用。结论局部冰敷对于早期眼睑痉挛可能起到抑制或减轻症状的作用，A型肉毒素局部注射对于持续时间较久的眼睑或面肌痉挛为一安全、有效、可靠的治疗手段并易于推广与普及。
Objective To observe the efficacy of using Botox-A in the treatment of blepharospasm （BS） and hemifaeial spasm （HFS）. Methods A total of 150 patients with BS and HFS were involved in the present study. Fifty patients who had the disease for less than six months were divided into two groups： one group （25 cases） was treated with a local ice-bag application and the other group （25 cases） was used for the control. One hundred patients who had a history of more than 6 months were. managed with a lo- cal injection of Botox-A. Results In the 25 patients treated with ice bags, symptoms completely disappeared in 23 patients and the remaining 2 patients presented with relieved spasm. Among the 25 cases used as the controls, the symptoms of 15 patients sponta- neously disappeared 1 to 2 months later, 7 patients presented with relieved spasm and the conditions of 3 patients remained un- changed. Ninety-eight of the 100 cases with BS and HFS whose history lasted more than 6 months had a complete or obvious re- mission of symptoms after receiving a local injection of Botox-A （BTA）, with no effect seen ＇after the treatment in the remaining 2 cases. No systemic toxic or side effects were found in any patients treated with a Botox-A injection. Conclusion Local ice-bag application contributes to the relief of BS and HFS in the early stages. A BTA local injection, which is easy to administer, is a safe, effective and reliable treatment for patients whose spasm has lasted for more than 6 months.
出处
《眼视光学杂志》
2009年第3期232-233,共2页
Chinese Journal of Optometry & Ophthalmology
