摘要
目的:探讨甲氯芬酯在急性酒精中毒治疗中的效果。方法:收集我院2005年1月1日-2007年12月31日收治的急性酒精中毒病人1716例中应用注射用盐酸甲氯芬酯的686例作为治疗组,而应用纳洛酮治疗的834例为对照组,通过对临床症状:动作协调性、中毒症状、谵妄、意识障碍程度等的改善程度进行两组治疗效果比较。结果:年龄分布、血清酒精浓度两组均数经t检验,显示两组无显著性差异(P>0.05)。入院时的临床表现分值经t检验无显著性差异。两组均达到临床治愈。结论:甲氯芬酯在临床治疗急性酒精中毒疗效上与纳洛酮相当。
Objective： To investigate the curative effect of Meclofenoxate hydrochloride in the treatment of acute alcohol intoxication. Methods： 1716 patients collected from suffered from acute alcohol intoxication in Xiamen Mental Health Center from 1 January, 2005 to 31 december, 2007, 686 patients used Meclofenoxate Hydrochloride for injection were the treatment group, and 834 patients used Naloxone were the control group. We compared the curative effect of these groups by the improvement of the clinic symptom （action coordination, toxicity symptom, delirium, disorders of consciousness,ect）. Results： There was no difference in t-test of the mean of the two group in age and alcohol concentration. There was no difference in t-test of clinic symptom that when they admittedThe two group were be healed. Conclusion： Both of Meclofenoxate Hydrochloride and Naloxone of were consistant with the curative treatment of acute alcohol intoxication.
出处
《中国药物滥用防治杂志》
CAS
2009年第3期141-143,共3页
Chinese Journal of Drug Abuse Prevention and Treatment
关键词
甲氯芬酯
急性酒精中毒
治疗
Meclofenoxate Hydrochloride
Acute alcohol intoxication
Treatment
