摘要
利用紫外光和核黄素相互作用引起的胶原交联,治疗进展期圆锥角膜,可增加角膜基质的机械强度,阻止圆锥角膜的进展,并可轻度提高视力。交联治疗的最大效应位于角膜前基质层300～340μm,对角膜内皮无明显损害。进一步的研究可能将此方法用于预防性治疗早期圆锥角膜,以期在阻止圆锥角膜进展的同时能更好地矫正视力。
Collagen crosslinking by ultraviolet A-light and riboflavin is an effective means for increasing corneal rigidity and preventing the progression of keratoconus. Visual acuity can be improved slightly. The maximum effect of the treatment locates in the anterior 300-340μm of the cornea. No statistically significant change is found for endothelial cell density. With more long-term research, prophylactic treatment of keratoconus at the early stage might become possible, preventing the development of keratoconus and additional refractive correction can be realized.
出处
《眼科》
CAS
2009年第3期150-152,共3页
Ophthalmology in China
关键词
紫外光
核黄素
交联
圆锥角膜
ultraviolet A-light
riboflavin
crosslinking
keratoconus
