摘要
目的:探讨颈动脉支架术后重度低血流动力状态的药物治疗方法及其效果。方法:回顾北京大学第一医院近5年颈动脉支架术围手术期发生重度低血流动力学状态患者的临床资料。重度低血流动力学状态是指围手术期动脉血压<90/60 mmHg(1 mmHg=0.133 kPa)或心率<50/min并持续1 h以上。本组共有13例。结果:13例患者静脉应用多巴胺维持血压,其中2例患者同时应用多巴酚丁胺。多巴胺用量2～10μg/(min.kg),多巴酚丁胺5～7μg/(min.kg),平均6μg/(min.kg),未发生永久性神经系统并发症,但有1例发生急性冠状动脉综合征。结论:颈动脉支架术围手术期重度低血流动力学状态应用血管活性药物(多巴胺,多巴酚丁胺)可以得到有效控制,并可防止相应并发症的发生。
Objective：To evaluate the efficacy of pharmaceutical therapy for the severe hemodynamic depression with carotid artery stenting（CAS） . Methods： Clinical data were retrospectively analyzed on CAS over the last 5 years. Severe hemodynamic depression was defined as periprocedural hypotension （blood pressure 〈 90/60 mmHg） or bradycardia （heart rate 〈 50 beats/rain） persisting for at least 1 hour. 13 patients were included in the research. Results： Dopamine was pumped intravenously in all the 13 patients. The dose was from 26μg/（min ·kg） to 10 6μg/（min · kg）, the duration was from 4 to 48 hours. Dobutamine was used in 2 patients and dose from 5 6μg/（min · kg） to 7 6μg/（min · kg）, duration was from 24 to 36 hours. None of the patients developed any permanent neurological complications. One acute coronary syndrome occured during the postprocedure period. Conclusion： Severe hemodynamic depression can he controlled with vasopressors （dopamine or dobutamine） and the associated complications can be prevented.
出处
《北京大学学报（医学版）》
CAS
CSCD
北大核心
2009年第3期373-375,共3页
Journal of Peking University:Health Sciences
关键词
颈动脉狭窄
支架
低血压
药物疗法
Carotid stenosis
Stents
Hypotension
Drug therapy
