摘要
目的采用MRI成像技术显示正常人眼球运动神经的颅内段、海绵窦段和眶内段的影像特征。方法正常受试者20名，年龄24～38岁，平均（28．25±4．07）岁。眼球运动神经脑池段采用头线圈，层厚0，8mm，3D—FIESTA序列扫描；海绵窦段采用头线圈，冠状面FSE，T1WI扫描，层厚2．0mm，层间距0．3mm；眼眶段采用表面线圈，冠状面FSE，T1WI扫描，层厚2．0mm，层间距0．3mm。对照火棉胶包埋0．1mm层厚，HE染色的完整眼眶冠状切片，在连续冠状MRI影像上追踪和分辨动眼神经、滑车神经和外展神经，直至分支进入相应的眼外肌。结果脑池段动眼神经和外展神经显示率为100％，滑车神经显示率为95％；海绵窦段动眼神经显示率100％，外展神经和滑车神经部分显示；在连续冠状的眼眶组织切片指引下，眶内段外展神经和动眼神经下支的分支完全显示，动眼神经上支显示60％，滑车神经显示40％。结论连续的薄层三维FIESTA序列扫描结合多平面重组技术，MRI能清晰地显示眼运动神经脑池段及其毗邻关系。MRI能清晰显示眶内动眼神经下支和外展神经。由于动眼神经上支和滑车神经结构精细，毗邻关系复杂，部分显示。对眼球运动神经路径上复杂的解剖结构的知识背景，影响分析MRI呈现的影像学信息。
Objective To display the detail functional anatomy of ocular motor nerves in the orbits, cavernous sinus and brainstem by high-resolution MRI. Methods Twenty normal subjects between 24 and 38 years of age, mean age was 28.25 ±4. 07 （SD）. Imging of the ocular motor nerves at the brainstem was performed in 0. 8 mm thickness image planes using 3D-FIESTA sequence; nerves in tbe cavernous sinus was imaged with a head coil, the FSE/T1WI was obtained in coronal planes; nerves to extraocular muscles （EOMs） in the orbits were imaged with FSE/T1WI oblique-coronal planes using surface coils, and within 2.0 mm thick planes. A human orbit was celloidin embedding and serially sectioned at 0. 1 mm of thickness for HE stain, which would be used to distinguish motor nerves to the EOMs. Results Oculomotor nerves （CN3） and abducens （CN6） of the cisternal segment were well demonstrable in all normal subjects. Trochlear nerves （CN4） were depicted 95%. CN3 could be demonstrated consistently in the cavernous sinus, because of their small diameter, CN4 and CN6 not always detectable. The larger inferior division of CN3 and branches to the target EOMs and CN6 were demonstrated well in all species. The superior division of CN3 was demonstrated 60%, CN4 was showed 40%. Conclusion 3D-FIESTA Seguence combined with MPR（ Muhiplanar Reformation） could precisely show the ocular motor nerves, as well as the relationships with adjacent stractures in the cistern. The inferior division of CN3 and the CN6 could be well depicted in the orbits. But of the small sizes and complecated neighboring structures in the orbit, the superior division of the CN3 and the CN4 could not be demonstrated consistently. The capabilities of MRI can be fully used only with thorough knowledge of the complicated topographic relationships in the corresponding region.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2009年第3期219-224,共6页
Chinese Journal of Ophthalmology
关键词
磁共振成像
动眼神经
展神经
滑车神经
Magnetic resonance imaging
Oculomotor nerve
Abducens nerve
Trochlear nerve
