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人肠道病毒71型的研究进展 被引量：7

Progress in Study on Human Enterovirus Type 71
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摘要 近年来,人肠道病毒71(EV71)感染在世界各地尤其是亚太地区呈上升趋势。EV71感染主要引起手足口病,但所致的神经系统并发症可导致死亡或永久性肌麻痹,已引起医学界的广泛关注。本文对EV71的病原学、流行病学、分子流行病学特征及实验室检测、预防和研究方向等作一综述。 In recent years, human enterovirus type 71 （EV71） infection shows an increasing tendency in the world especially in Asia-Pacific area. EV71 infection mainly causes hand, foot and mouth disease which may result in central nervous system （CNS） complication related to fatality and permanent muscle paralysis, thus has been paid widespread attention. This paper reviews the etiological, epidemiological and molecular epidemiological characters, laboratory examination, prevention as well as orientation of research of EV71.
作者 常宏伟 王明丽
机构地区 安徽省六安市疾病预防控制中心 安徽医科大学微生物学教研室
出处 《中国生物制品学杂志》 CAS CSCD 2009年第6期613-617,共5页 Chinese Journal of Biologicals
关键词 肠道病毒71 流行病学 实验室检测 Enterovirus 71 Epidemiology Laboratory examination
分类号 R373.2 [医药卫生—病原生物学]
  • 相关文献

参考文献42

  • 1Yang TT, Huang LM, Lu CY, et al. Clinical features and facters of unfavorable outcomes for non-polio enterovirus infection of the centeral nervous system in northern Taiwan, 1994-2003. J Microbiol Immunol Infect, 2005, 38(6): 417-424.
  • 2Arita M, Ami Y, Wakita T, et al. Cooperative effect of the attenuation determinants derived from poliovirus Sabin 1 strain is essential for attenuation of enterovirus 71 in the NOD/SCID mouse infection model. J Virol, 2008, 82(4): 1787-1797.
  • 3严志平,何雅青,刘可,何建凡,张顺祥.深圳市南山区肠道病毒71型引起手足口病局部流行的初步调查[J].中国公共卫生,2001,17(7):645-645. 被引量：35
  • 4Schmidt N J, Lennett EH, Ho HH. An apparently new enterovirus isolated from patients with disease of the centeral nervous system. J Infect Dis, 1974, 129 (3): 304-349.
  • 5Huang YP, Lin TL, Kuo CY, et al. The circulation of subgenogroups B5 and C5 of enterovirus 71 in Taiwan from 2006 to 2007. Virus Res, 2008, 137 (2): 206-212.
  • 6Brown BA, Oberste MS, Alexander JP Jr, et al. Molecular epidemiology and evolution of enterovirus 71 strains isolate from 1970 to 1998. J Virol, 1999, 73 (12): 9969-9975.
  • 7Hamaguchi T, Fujisawa H, Sakai K, et al. Acute encephalitis caused by intrafamilial transmission of enterovirus 71 in adult. Emerg Infet Dis, 2008, 14 (5): 828-830.
  • 8Shih SR, Ho MS, Lin KH, et al. Genetic analysis of enterovirus 71 isolated from fatal and non-fatal cases of hand,foot and mouth disease during an epidemic in Taiwan, 1998. Virol Res, 2000, 68 (2): 127-136.
  • 9McMinn P, Lindsay K, Perera D, et al. Phyogenetic analysis of enterovirus 71 strains isolated during linked epidemics in Malasia, Singpore,and Western Australia. J Virol, 2001, 75( 16): 7732-7738.
  • 10Chan YF, AbuBakar S. Human enterovirus 71 subgenotype B3 lacks coxsackievirus A16-like neurovirulence in mice infection. J Virol, 2005, 2: 74.

二级参考文献16

  • 1于长水.天津市由CoxA16肠道病毒引起的手足口病流行[J].中华流行病学杂志,1985,6(2):66-69.
  • 2Kovarova H, Stulik J, Macela A, et al. Using two-dimensional gel electrophoresis to study immune response against intracellular bacterial infection [J]. Electrophoresis, 1992, 13(9- 10) : 741-742.
  • 3Tosifusa T, Masanobu S. Proteome analysis of Epstein-Barr virustransformed B-lymphoblasts and the proteome database [J]. J Chromatogr B Analyt Technol Biomed Life Sci , 2003, 787 ( 1 ):197 - 206.
  • 4Schmidt N J, Lennette E H, Ho H H, et al. An apparently new enterovirus isolated from patients with disease of the central nervous system [J]. J Infect Dis, 1974, 129(3) : 304- 309.
  • 5Ishimaru Y, Nakano S, Yamaoka K, et al. Outbreaks of handfoot-and-mouth disease by enterovirus 71 [J]. Arch Dis Child,1980, 55(8) :583 - 588.
  • 6Gilbert G L, Dickson K E, Waters M J, et al. Outbreak of enterovirus 71 infection in Victoria, Australia, with a high incidence of neurologic involvement[J]. Pediatr. Infect Dis, J, 1988, 7(7): 484 -488.
  • 7Kennett M L, Birch C J, Lewis F A, et al. Enterovirus type 71infection in Melbourne[J]. Bull World Health Organ, 1974, 51(6) :609-615.
  • 8Komatsu H, Shimizu Y, Takeuchi Y, et al. Outbreak of severe neurologic involvement associated with enterovirus 71 infection[J]. Pediatr Neurol, 1999 , 20(1) :17 - 23.
  • 9Ho M, Chen E R, Hsu K H, et al. An epidemic of enterovirus 71 infection in Taiwan [J]. New Engl J Med, 1999,341(13): 929-935.
  • 10Lum L C, Wong K T, Lam S K, et al. Fatal enterovirus 71 encephalomyelitis[J]. J Pediatr, 1998,133(6): 795 798.

共引文献37

同被引文献65

  • 1张淑子,李凡,易世红.重组人干扰素α2a凝胶对单纯疱疹病毒感染的疗效[J].中国生物制品学杂志,2006,19(6):607-609. 被引量：4
  • 2董晓楠,应剑,陈应华.1970～2004年全球肠道病毒71型分离株的分子流行病学分析[J].科学通报,2007,52(9):1021-1027. 被引量：108
  • 3Zhang Y, Tan X J, Wang HY, et al. An outbreak of hand, foot, and mouth disease associated with subgenotype C4 of human enterovirus 71 in Shandong, China. J Clin Virol, 2009, 44 (4): 262- 267.
  • 4Chen SC, Chang HL, Yah TR, et al. An eight-year study of epidemiologic features of enterovirus 71 infection in Taiwan. Am J Trop Med Hyg, 2007, 77 (1): 188-191.
  • 5McMinn P, Lindsay K, Perera D, et al. Phylogenetic analysis of enterovirus 71 strains isolated during linked epidemics in Malaysia, Singapore, and Western Australia. J Virol, 2001, 75 (16): 7732- 7738.
  • 6Shih SR, Ho MS, Lin KH, et al. Genetic analysis of enterovirus 71 isolated from fatal and non-fatal cases of hand, foot and mouth disease during an epidemic in Taiwan, 1998. Virus Res, 2000, 68 (2): 127-136.
  • 7Foo DG, Macary PA, Alonso S, et al. Identification of human CD4+ T-cell epitopes on the VP1 capsid protein of entemvirus 71. Viral Immunol, 2008, 21 (2): 215-224.
  • 8Chen HL, Huang JY, Chu TW, et al. Expression of VP1 protein in the milk of transgenic mice: a potential oral vaccine protects against enterovirus 71 infection. Vaccine, 2008, 26(23): 2882-2889.
  • 9何金生.人轮状病毒重要抗原在重组腺病毒中表达与免疫效果研究.北京:中国预防医学科学院,2001.
  • 10Hu YC, Hsu JT, Huang JH, et al. Formation of enterovirus-like particle aggregates by recombinant baculoviruses co-expressing P1 and 3CD in insect ceils. Biotechnol Lett, 2003, 25 (12): 919-925.

引证文献7

二级引证文献43

中国生物制品学杂志
2009年 第6期

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