摘要
目的:评估外科治疗在原发性肺低分化B细胞淋巴瘤诊治中的价值。方法:1997年3月—2007年3月共28例高度怀疑为原发性肺低分化B细胞淋巴瘤的患者进行了外科手术治疗,术后对部分患者进行了化疗和放疗。对手术标本进行病理学诊断,并进行临床分期。对患者进行随访,绘制生存曲线。结果:本组28例患者均经术后病理诊断为原发性肺低分化B细胞淋巴瘤。接受根治性手术患者的5年生存率为90.0%,高于非根治性手术患者的5年生存率28.6%(P<0.05)。结论:原发性肺低分化B细胞淋巴瘤是一种罕见的疾病,外科手术对原发性肺低分化B细胞淋巴瘤的诊断具有十分重要的意义,行根治性手术可显著延长患者的生存期。
Objective：The purpose of this study was to determine the role of surgery in the diagnosis and treatment of primary pulmonary low differentiated B cell lymphoma （PPLBL）. Methods：Twenty eight patients who had highly doubtful PPLBL received surgery in our hospital between March 1997 to March 2007. Some patients received chemotherapy and radiotherapy after surgery. We performed pathological examinations on the surgical specimens and evaluated the clinical stage. Then we followed up these patients and drew the growth curve. Results：The study included 28 patients with PPLBL which was confirmed by pathological examination post surgery. All of the 28 cases of PPLBL belonged to the non-Hodgkin＇ s lymphoma. The 5-year survival rate of the patients who received complete resection surgery was 90% , which was significantly higher than those who did not receive resection surgery （28.6%, P 〈 0.05）. Gender, bilateral disease, or adjuvant therapy did not affect survival rate. Conclusion： PPLBL is a rare disease that may be localized or diffuse in one or both lungs. Surgery was important for the diagnosis of PPLBL. A complete resection could prolong the longterm survival period of PPLBL patients.
出处
《肿瘤》
CAS
CSCD
北大核心
2009年第6期582-584,共3页
Tumor
基金
上海市科学技术委员会引导项目(编号:074119646)
关键词
淋巴瘤
B细胞
肺肿瘤
诊断技术
外科学
预后
Lymphoma, B-cell
Lung neoplasms
Diagnostic techniques, surgical
Prognosis
