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单纯疱疹病毒胸苷激酶在自杀基因治疗中的研究 被引量:1

Research of herpes simplex virus-thymidine kinase in suicide gene therapy
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摘要 单纯疱疹病毒-胸苷激酶(HSV-TK)目前已进行了恶性脑瘤、卵巢癌、前列腺癌等肿瘤的临床试验。结果表明,该基因疗法能够提高患者生活质量,延缓肿瘤生长、复发和转移,且无明显不良反应。 Therapeutic efficacy and security of herpes simplex virus-thymidine kinase(HSV-TK) gene therapy has been evaluated by the treatment of malignant cerebroma, ovarian cancer, prostate cancer and etc. The results show that HSV-TK gene therapy can improve patients life quality, delay cancer growth, recurrence and metastasis, and it has no obvious side effects.
出处 《国际肿瘤学杂志》 CAS 2009年第6期409-411,共3页 Journal of International Oncology
基金 国家自然科学基金资助项目(30672405)
关键词 基因疗法 胸苷激酶 临床试验 Gene therapy Thymidine kinase Clinical trials
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