摘要
单纯疱疹病毒-胸苷激酶(HSV-TK)目前已进行了恶性脑瘤、卵巢癌、前列腺癌等肿瘤的临床试验。结果表明,该基因疗法能够提高患者生活质量,延缓肿瘤生长、复发和转移,且无明显不良反应。
Therapeutic efficacy and security of herpes simplex virus-thymidine kinase(HSV-TK) gene therapy has been evaluated by the treatment of malignant cerebroma, ovarian cancer, prostate cancer and etc. The results show that HSV-TK gene therapy can improve patients life quality, delay cancer growth, recurrence and metastasis, and it has no obvious side effects.
出处
《国际肿瘤学杂志》
CAS
2009年第6期409-411,共3页
Journal of International Oncology
基金
国家自然科学基金资助项目(30672405)
关键词
基因疗法
胸苷激酶
临床试验
Gene therapy
Thymidine kinase
Clinical trials