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白细胞介素-6基因多态性及其与卵巢肿瘤的相关性

IL-6 gene polymorphism and its relationship with ovarian neoplasms
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摘要 临床研究发现，卵巢肿瘤患者白细胞介素（IL）-6水平明显升高，其升高能促进卵巢肿瘤的发生。IL-6升高可能是由于IL-6基因多态性影响其转录和表达。然而IL-6基因多态性与卵巢肿瘤是否具有相关性，目前尚存争议。 Clinical studies find that the level of IL-6 is significantly up-regulated in ovarian neoplasms patients. It can promote the carcinogenesis of ovarian. The up-regulation of IL-6 may be correlated with the IL- 6 gene polymorphism which affects its transcription and expression. However, there is disputation in association between IL-6 gene polymorphism and ovarian neoplasms.
作者 曲爱忠 梁婧 刘晓琳(综述) 李岩(审校)
机构地区 山东大学山东省千佛山医院肿瘤科
出处 《国际肿瘤学杂志》 CAS 2009年第6期472-473,共2页 Journal of International Oncology
基金 山东省科技厅自然基金项目（2005ZX04）
关键词 白细胞介素6 多态性 单核苷酸 卵巢肿瘤 Interleukin- 6 Polymorphism, single nueleotide Ovarian neoplasms
分类号 R737.31 [医药卫生—肿瘤]
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参考文献9

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二级参考文献8

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国际肿瘤学杂志
2009年 第6期

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