摘要
目的评价原发性肝癌根治性切除术后肝动脉灌注化疗与门静脉灌注化疗的疗效，探讨原发性肝癌根治性切除术后复发及转移的预防途径。方法经病理确诊的原发性肝癌７５例，其中４２例行根治性切除及术后选择性肝动脉插管化疗，３３例行根治性切除及术后门静脉灌注化疗。每隔１～３个月重复，定期复查。结果原发性肝癌切除术后肝动脉灌注化疗组的术后复发率（２１．４３％）低于门静脉灌注化疗组（３６．３６％），且生存时间（１１．４个月）明显较门静脉灌注化疗组（７．６个月）长，而门静脉灌注化疗组的转移率（９．０９％）明显低于肝动脉灌注化疗组（３２．１４％）。结论原发性肝癌根治性切除术后行肝动脉灌注化疗较门静脉灌注化疗疗效好，而原发性肝癌切除术后同时结合肝动脉。
URPOSE To evaluate the therapeutic efficacy of hepatic arterial and portal venous infusion chemotherapy after hepatic resection and to study ways of preventing recurrence and metastases of primary liver cancer after hepatic resection.METHODS In 75 patients with primary liver cancer,42 cases received hepatic arterial infusion chemotherapy after hepatic resection.Infusion chemotherapy was done at 1～3 monthly intervals,examined at regular intervals and were followed up till June 1996.RESULTS The results indicated that the percentage of recurrence of the hepatic arterial infusion chemotherapy group (2143%) was lower than that of the portal venous infusion chemotherapy group (3636%),but the percentage of metastasis of the hepatic arterial infusion chemotherapy group (3214%) was higher (the latter was 909%).The average survial time of hepatic arterial infusion chemotherapy group (114 months) was much longer than that of portal venous infusion chemotherapy (76 months).CONCLUSION The treatment of the hepatic arterial infusion chemotherapy had better results than that of portal venous infusion chemotherapy after hepatic resection of primary liver cancer,but combined hepatic arterial and portal venous infusion chemotherapy was better for preventing recurrence and metastasis of primary liver cancer after hepatic resection.
出处
《中国癌症杂志》
CAS
CSCD
1998年第2期102-104,共3页
China Oncology
关键词
肝肿瘤
肝切除
肝动脉输注
门静脉输注
药物疗法
Liver neoplasms Hepatectomy Hepatic artery infusion Portal vein infusions
