摘要
目的探讨特发性颅内压增高综合征(idiopathic intracranial hypertension,IIH)与颅内静脉窦病变的相关性。方法回顾性分析2004年-2008年北京市海淀医院及北京同仁医院收治的36例临床疑诊IIH患者的临床表现、影像学表现及血栓危险因素等临床资料。结果本组36例均为亚急性发病。首发症状视力障碍29例,头痛7例。伴随症状包括,波动性颅鸣1例(2.8%),眼胀痛2例(5.6%),头晕4例(11.1%),外展神经麻痹4例(11.1%)。按脑血管造影(DSA)结果分3组,颅内静脉窦闭塞15例(41.7%),狭窄组11例(30.5%),正常组10例(27.8%)。3组患者中有血栓危险因素者分别占80%、45.4%、30%,闭塞组与狭窄组和正常组之间比较均有显著性差异(P<0.05)。结论IIH患者静脉窦狭窄发生率高,静脉窦闭塞与血栓危险因素相关。
Objective To explore the correlation between idiopathic intracranial hypertension （IIH） and cerebral venous sinus disease. Methods Thirty - six patients with presumed IIH admitted from 2004 to 2008 were retrospectivly analysed for clinical feature, radiographic finding and risk factors of thrombosis. The correlation between IIH and cerebral venous sinus disease was investigated. Results The study population included 10 men and 26 women with an average age of 37.1 years （from 22 to 53）. The course of disease was from 2 months to 36 months with an average of 7.0 months （ standard deviation, 9.1 ）. The initial syndrome was visual disturbance in 29（80.6% ） and headache in 7（ 19.4% ）, other symptoms included pulsatile intracranial noises, eye pain, dizzness or the sixth cranial nerve palsy. All patients were divided into three groups according to DSA,including cerebral venous thrombosis in 15 （41.7%）, cerebral venous stenoses in 11 （30. 5% ） and normal cerebral venous in 10（27.8% ）. A quite different distributions of risk factors for thrombosis was presented between cerebral venous thrombosis group and others （ P 〈 0.05 ）. Conclusions This study has shown a high prevalence of cerebral venous stenoses in patients with IIH. Cerebral venous sinus thrombosis is correlated with the risk factors for thrombesis.
出处
《北京医学》
CAS
2009年第7期389-392,共4页
Beijing Medical Journal
关键词
特发性颅内压增高综合征
静脉窦狭窄
静脉窦闭塞
Idiopathic intracranial hypertension Cerebral venous stenoses Cerebral venous thrombosis
