肌胺肽苷注射液联合心理干预对伴焦虑抑郁障碍冠心病介入治疗患者的疗效观察被引量：4

下载PDF

导出

摘要目的：探讨伴焦虑抑郁障碍冠心病患者接受介入治疗前后情况以及肌胺肽苷注射液联合心理干预的效果。方法：采用Zung抑郁自评量表（SDS）、焦虑自评量表（SAS）对201例拟接受冠脉介入治疗的冠心病患者进行焦虑抑郁障碍调查评分。将201例患者随机分为联合干预组和对照组,干预组在手术前1－2d和手术后7－10d静点肌胺肽苷注射液,同时于上述时段以及术后3月、6月、12月、24月给予心理干预,对照组常规治疗并于同样时间进行焦虑抑郁评定和心理干预。结果：术前两组患者抑郁发生率、SDS评分无显著差异。术后干预组的抑郁障碍较对照组有明显改善（SDS评分分别为36.54±4.25和46.17±6.42,P〈0.01）,手术前后干预组抑郁发生率无明显差异,而对照组术后抑郁发生率明显高于手术前（SDS评分分别为46.54±6.25和73.46±6.73,P〈0.01）,干预组出院后24个月内再住院、心血管事件发生率明显低于对照组,生活质量提高明显高于对照组。多因素分析显示：教育水平低下、近期负性生活事件、社会经济地位、病程绵长、导管介入治疗后遗症与冠心病抑郁之间存在明显相关（P〈0.01）;且抑郁程度与患者出院后恢复、恶性心血管事件发生之间存在明显相关（P〈0.01）。结论：肌胺肽苷注射液联合心理干预可以有效减轻抑郁焦虑障碍和降低心血管事件的发生,提高患者的生活质量。

作者李方江房春林徐涛王亚玲袁桂莉李会贤赵久安李跃师素芳

机构地区河北北方学院附属第一医院心内科河北省崇礼县医院河北省怀来县医院

出处《河北北方学院学报（医学版）》 2009年第3期48-50,共3页 Journal of Hebei North University:Medical Edition

基金河北省科学技术研究与发展指导计划(编号:072761560)

关键词冠心病介入治疗抑郁焦虑心理干预肌胺肽苷注射液

分类号 R541.4 [医药卫生—心血管疾病]

引文网络
相关文献

参考文献13

1Holt-Lunstad J,Birmingham W,Jones BQ.Is there something unique about marriage? The relative impact of marital status,relationship quality,and network social support on ambulatory blood pressure and mental health[J].Ann Behav Med,2006,35(1):45-51
2Chaput JP,Arguin H,Gagnon C.Increase in depression symptoms with weight loss:association with glucose homeostasis and thyroid function[J].Appl Physiol Nutr Metab,2007,33(1):86-92
3Rangan C,Everson G,Cantrell FL.Central alpha-2 adrenergic eye drops:case series of 3 pediatric systemic poisonings[J].Pediatr Emerg Care,2006,24(3):167-169
4Allen M,Iezzoni LI,Huang A,et al.Improving patient-clinician communication about chronic conditions:description of an internet-based nurse E-coach intervention[J].Nurs Res,2005,57(2):107-112
5Rivara FP,Mackenzie EJ,Jurkovich GJ.Prevalence of pain in patients 1 year after major trauma[J].Arch Surg,2005,143(3):282-287
6Ronis DL,Duffy SA,Fowler KE.Changes in quality of life over 1 year in patients with head and neck cancer[J].Arch Otolaryngol Head Neck Surg,2006,134(3):241-248
7Monami M,Longo R,Desideri CM.The diabetic person beyond a foot ulcer:healing,recurrence and depressive symptoms[J].Am Podiatr Med Assoc,2008,98(2):130-136
8Cluver LD,Gardner F,Operario D.Effects of stigma on the mental health of adolescents orphaned by AIDS[J].J Adolesc Health,2007,42(4):410-417
9Solorio MR,Rosenthal D,Milburn NG.Predictors of sexual risk behaviors among newly homeless youth:a longitudinal study[J].J Adolesc Health,2008,42(4):401-409
10Yang HJ,Chiu YJ,Soong WT.The roles of personality traits and negative life events on the episodes of depressive symptoms in nonreferred adolescents:a 1-year follow-up study[J].J Adolesc Health,2008,42(4):378-385