期刊文献+

控制心血管病人术中心率抗术后心肌缺血的作用研究

The Influence of Controlling Heart Rate on Postoperative Myocardial Ischemia in Patients with Cardiovascular Disease During Noncardiac Surgery
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摘要 目的研究心血管疾患病人接受非心脏手术时,术中调控患者心率低于术前水平,对术后3d发生心肌缺血的影响.方法选择71例行腹部手术的患者,年龄55~78岁,随机分为对照组和实验组.对照组(n=36)术中维持心率于术前平均水平,实验组(n=35)较术前降低10%~20%,所有病人行术前1d、术中以及术后3dHolter监测,比较两组间心率、ST段变化情况.结果实验组心率术后和术前相比,差异无统计学意义(P>0.05),而对照组心率术后第1天、第2天较术前增快,且术后第1天高于实验组(P<0.05);对照组术后有20人(55.6%)发生心肌缺血,实验组术后有9人(27.3%),两组间心肌缺血的发生率差异有统计学意义(P<0.05).结论心血管疾患病人行非心脏手术,术中一定范围内降低心率,有利于稳定术后心率,减少术后心肌缺血的发生. Objective To investigate the influence of controlling heart rates on postoperative myocardial ischemia in patients with cardiovascular disease during noncardiac surgery, especially in 3 days after surgery. Methods Eight-seven patients aged 55 - 78 yrs undergoing noncardiac surgery were devided into two groups at random: control group (group Ⅰ , n = 36) and management group (group Ⅱ , n = 35). The heart rates of patients in management group were degraded 10% - 20% during operation than before operation. Holter was used to monitor all of the patients' heart rate and myocardial ischemia, during one day before operation, operation and 3 days after operation. The index of holter was recorded and compared. Results There was no significant difference between postoperative and preoperative in group Ⅱ (P 〉 0.05) , but significant difference in group Ⅰ and between group Ⅰ and group Ⅱ during the first postoperative day (P 〈 0.05). 3 days affer operation, twenty patients in group I and five patients in group Ⅱ developed myocardial ischemia. There was significant difference between the two groups (P〈 0.05). Conclusion Controlling heart rates of patients with cardiovascular disease during anesthesia can keep constant heart rates and show reduced incidence of postoperative myocardial ischemia.
出处 《昆明医学院学报》 2009年第7期116-120,共5页 Journal of Kunming Medical College
关键词 非心脏手术 心率 心肌缺血 Noncardiac surgery Heart rate Myocardial ischemia
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参考文献10

  • 1PRIEBE H J.Triggers of preoperative myocardial is chaemia and infarction[J].Br j Anaesth,2004,93 (1):9-20.
  • 2幸志强,曾旭初,易春涛,袁峰,朱志雄.丹参对冠心病患者血清脂质过氧化物及超氧化物歧化酶的影响[J].中国中西医结合杂志,1996,16(5):287-288. 被引量:121
  • 3HALLIBURTON B,BELL D,PRESTON J,et al.ACC/AHA Guideline update for perioperative cardiovascular evaluation for noncardiac surgery:executive summary a report of the american college of cardiology/american hart association task force on practice guidelines (committee to update the 1996 guidelines on perioperative cardiovascular evaluation for noncardiac Surgery)[J].Circulation,2002,105:1257-1267.
  • 4曾因明,邓小明,主译.米勒麻醉学[M].第6版.北京:北京大学医学出版社,2006:410-411.
  • 5SPRUNG J,WARNER M E,CONTREAS M G,et al.Predictors of survival following cardiac arrest in patients undergoing noncardiac surgery:a study of 518 294 patients at a tertiary referral center[J].Anesthesiology,2003,99:259-269.
  • 6UDELSMAN R,NORTON J A,JELENICH S E,et al.Responses of the hypothalamic-pituitary-adrenal and rennin-angiotensin axes and the sympathetic system during controlled surgical and anesthetic stress[J].J Clin Endocrinol Metab,1987,64:986-994.
  • 7OLIVER M F,OPIE L H.Effects of glucose and fatty acids on myocardial ischaemia and arrythmias[J].Lancet,1994,343:155-158.
  • 8LOPEZ-SENDON J,SWEDBERG K,MCMURRAY J,et al.Expert consensus document on beta-adrenergic receptor blockers[J].Eur Heart J,2004,25:1341-1362.
  • 9刘玲玲,王士雯,谭端军,申俊梅,刘鹏.非心脏手术围手术期心肌缺血与心脏事件的相关因素[J].实用老年医学,2001,15(1):17-19. 被引量:21
  • 10DEVEREAUX P J,GOLDMAN L,COOK D J,et al.Perioperative cardiac events in patients undergoing noncardiac surgery:a review of the magnitude of the problem,the pathophysiology of the events and methods to estimate and comvunicate risk[review][J].CMAJ,2005,173 (6):627-634.

二级参考文献12

  • 1[1]Goldman L.Cardiac risk in noncardiac surgery:a update.Anesth Analg,1995,80(4):810
  • 2[2]ACC/AHA Task force on practice guidelines.ACC/AHA Guidelines for perioperative cardiovascular evaluation for noncardiac surgery.Circulation,1996,96(6):1280
  • 3[3]Landesberg G,Luria MH,Cotev S,et al.Importance of long-duration postoperative ST-segment depression in cardiac morbidity after vascular surgery.Lancet,1993,341(8847):715
  • 4[4]Fleisher LA,Rosenbaum SH,Nelson AH,et al.The predictive value of preoperative silent ischemia for postoperative ischemic cardiac event in vascular and nonvascular surgical patients.Am Heart J,1991,122(4):980
  • 5[5]Coley CM,Eagle KA.Preoperative assessment and perioperative management of cardiac ischemic risk innoncardiac surgery.Curr Probl Cardiol,1996,21(5):289
  • 6杨霞芳,临床心血管病杂志,1992年,8卷,3期,145页
  • 7范东,中华实验外科杂志,1992年,9卷,增刊,253页
  • 8王惠嫒,中华医学杂志,1988年,68卷,1期,44页
  • 9陈可冀,心脑血管疾病研究,1988年
  • 10陈安忠,临床心血管病杂志,1992年,8卷,增刊,34页

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