摘要
目的:观察恶性胸腺瘤患者的手术疗效,并分析其与肿瘤分期、放疗、L/B病理分型及与预后的关系。方法:对63例恶性胸腺瘤患者进行手术治疗并辅以放疗,并按不同术式、Masaoka外科-病理分期、L/B病理分型比较,采用多因素Logistic回归分析其与预后的关系。结果:接受根治性手术,Masaoka外科-病理分期较早的患者3、5年生存率较高(P<0.05)。术后加用放射性治疗与否也与3、5年生存率有关系。不同病理(L/B)类型的患者,3、5年生存率差别无统计学意义。结论:恶性胸腺瘤患者早期手术并辅以放疗可提高生存率;Masaoka外科-病理分期和预后密切相关;L/B病理分型与预后无明显相关性。
Objective:To observe the clinical outcome of surgical treatment for malignant thymoma,and evaluate the prognostic factors thereof. Methods:All patients (63 cases)were operated and followed by radiotherapy. The Logistic regression analysis was used for the relationship between the prognosis, Masaoka staging, LfB pathology, and the differences of the operation given.Results:Patients with early Masaoka stage and who received radical resection of thymoma had higher 3 and 5 year survival rates (P 〈 0.05).The radiotherapy after surgery was related to 3 and 5 year survival rates. The differences of L/B pathology was not related to 3 and 5 year survival rates.Conclusion :The survival rate is enhanced for patients with malignant thymoma when both surgical and radiotherapy intervention are given as early as possible.The Masaoka staging, not L/B pathology, is closely related to the prognosis.
出处
《天津医药》
CAS
北大核心
2009年第7期568-570,共3页
Tianjin Medical Journal
关键词
胸腺瘤
外科手术
放射疗法
肿瘤分期
预后
thymoma surgical procedures, operative radiotherapy neoplasm staging prognosis