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^(18)F-fallypride-新型多巴胺受体显像剂在脑神经疾病研究中的临床应用 被引量：2

^(18)F-fallypride-new dopamine receptor imaging agent Clinical Application
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摘要 18F-Fallypride是一种新型安全的多巴胺D2受体PET显像剂,具有亲和力高、亲脂性适宜、半衰期短等特点,本文综述18F-Fallypride用于精神分裂症、癫痫、抽动秽语综合征、兴奋剂成瘾性等的多巴胺D2/D3受体变化的研究。 ^18F - Fallypride is a new security dopamine D2 receptor PET imaging agent, with the characteristics of high affinity, appropriate lipophilicity, short half- life. This paper reviews ^18 F -Fallypride applied on dopamine D2/D3 receptor studies such as schizophrenia, epilepsy, Tourette syndrome, stimulants addicts.
作者 许飞 杨敏 徐宇平 潘栋辉
机构地区 南京医科大学 南京医科大学附属无锡妇幼保健院 江苏省原子医学研究所卫生部核医学重点实验室
出处 《中国优生与遗传杂志》 2009年第7期129-131,共3页 Chinese Journal of Birth Health & Heredity
基金 江苏省高技术研究计划(BG2006604) 国家自然基金(30670714) 江苏省卫生厅面上项目(H200334) 江苏省医学重点人才资助(RC2007096)
关键词 ^18F-Fallypride PET 多巴胺D2/D3受体 显像剂 ^18F- Fallypride PET D2/D3 dopamine receptor Imaging agent
分类号 R817.4 [医药卫生—影像医学与核医学] R741 [医药卫生—神经病学与精神病学]
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参考文献11

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  • 2Buchsbaum MS,Christian BT,et al.D2/D3 dopamine receptor binder with[F-18]fallypride in thalamus and cortex of patients with schizophrenia[J].Schizophr Res,2006 Jul,85 (1-3):232-44.
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  • 7Konrad J.Werhahn,et al.Decreased Dopamine D2/D3 -Receptor binding in Temporal Lobe Epilepsy:An[18F] Fallypride PET study[J].Epilepsia,2006 Ang,47(8),1392-1396.
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二级参考文献14

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共引文献20

同被引文献13

引证文献2

二级引证文献6

中国优生与遗传杂志
2009年 第7期

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