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碘硒缺乏地区甲状腺肿患者甲状腺自身抗体的观察

Assessment of thyroid autoantibodies in patients with endemic goiter in combined iodine and selenium deficiency area.
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摘要 59例地方性甲状腺肿患者分为碘硒双补组及单纯补碘组。采用放射免疫法于防治前、后分别测定两组患者血清TGA、TMA。防治前上述两组血清TMA分别为23.28±22.8%,19.37±18.84%,防治后两组血清TGA、TMA显著下降(P<0.01)。结果提示地方性甲状腺肿患者中可能存在着自身免疫性甲状腺疾病;在碘硒缺乏地区。 おifty-nine patients with endemic goiter were divided into simple iodine supplementation and combined iodine and selenium supplementation groups.Serum TGA,TMA titers were measured by a radioimmunoassay before and after the control.Before control the serum TGA,TMA titers of two groups were 23.28±22.8%,19.37±18.84%,respectively.After contol the serum TGA,TMA titers of two groups were decreased markedly (P<0.01).The results suggested that (1) It is probable that autoimmune thyroid diseases existed in the patients with endemic goiter;(2) In iodineselenium deficient area,combined iodine and selenium supplementation has regulative effect on thyroid autoimmunity.
出处 《中国地方病学杂志》 CAS CSCD 1998年第4期247-248,共2页 Chinese Jouranl of Endemiology
关键词 地方性 甲状腺肿 TGA TMA Iodine and selenium deficiency Endemic goiter TGA TMA
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