摘要
目的:研究牙周炎患者唾液中一氧化氮(NO)含量与牙周炎各种临床指标的相关性,探讨一氧化氮在牙周炎发展过程中可能发挥的作用。方法:选择牙周健康者28人(对照组),慢性牙周炎32人(实验组),用G riess反应测定牙周基础治疗前后唾液中亚硝酸盐含量,间接反映NO水平,分析牙周临床指标与NO含量的关系。结果:实验组唾液中NO含量较对照组显著增加,牙周炎患者唾液NO含量与牙周探诊深度,附着水平之间有显著正相关。结论:NO的产生与牙周炎症过程有关。牙周基础治疗后,随着局部炎症逐渐减轻,唾液NO含量呈下降趋势。
AIM： To study the possible role of NO in the development of periodontitis. METHODS： We have analysed salivary NO2^- concentration in 32 subjects with chronic periodontitis and in 28 periodontally healthy persons. The concentrations of NO2^- were determined by the Griess reaction around scaling and root planning treatment, which reflected NO level indirectly . The changes of clinical indices（ SBI, PD and AL） were monitored. Then the rela- tionship between the NO level in saliva and the periodontal index was analyzed. RESULTS： Subjects with periodontitis had significantly higher NO concentrations in saliva than healthy subjects. Significant relationship was found between the attachment level, probing depth and NO concentration in saliva. CONCLUSION ： The production of NO in saliva may be correlated to the period of disease, and the local NO plays a role in the pathophysiology of periodontitis. After scaling and root planing, the degree of local inflammation is improved obviously, and the concentrations of NO in the saliva of patients with periodontal disease gradually decrease.
出处
《牙体牙髓牙周病学杂志》
CAS
北大核心
2009年第7期393-396,共4页
Chinese Journal of Conservative Dentistry
关键词
一氧化氮
唾液
牙周炎
nitric oxide
saliva
periodontitis
