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抗甲协定方联合西药治疗甲状腺机能亢进的临床研究 被引量:10

Effect of Combined Therapy of Modified Kangjia Recipe and West Medicine on Hyperthyroidism
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摘要 目的:观察抗甲协定方加减联合丙基硫氧嘧啶治疗甲状腺机能亢进症(简称甲亢)患者的临床疗效,评价其对甲亢的治疗作用及优势。方法:选取符合西医和中医诊断标准的甲亢患者100例,随机分为综合组50例,采用抗甲协定方加减合丙基硫氧嘧啶治疗,对照组50例,单用丙基硫氧嘧啶治疗;疗程均为3个月;观察两组治疗前后血清甲状腺激素、中医症状、体征改善情况及不良反应。结果:两组治疗后甲状腺激素水平、症状、体征均有明显改善(P<0.05),综合组有效率94%,对照组有效率80%,综合组优于对照组(P<0.05);不良反应发生率综合组少于对照组(P<0.05)。结论:抗甲协定方加减联合西药治疗甲亢优势明显。 Objective:To observe the therapeutic effect of combined therapy of modified Kangjia Recipe(KR) and propylthiouraeil( PTU)on hyperthyroidism and to assess its advantage. Methods :100 patients with hyperthyroidism were divided into the comprehensive treatment group(CTG) and the control group(CG) at random. The 50 patients in CTG treated with KR and PTU,and the 50 parle/its in CG treated with trl'U alone. The treatment course of both groups was 3 months. The serum thyriodhormone(TH) level, clinical symptoms signs, and adverse reactions were observed before and after treatment. Resu/ts :The serum TH level,clinical,symptoms and signs were signifieantly improved after treatment in both groups( all P 〈 0. 05). The total effective rate was 94% in CTG, which was higher than that in CG(80% ,P 〈0. 05). As for the incidence of adverse reaction,it was lower in the CTG then in the CG. Conclusion :The combined treatment of KR and Western medicine has good efficacy in treating hyperthyroidism.
作者 张丹 杨宏杰
出处 《辽宁中医杂志》 CAS 北大核心 2009年第7期1168-1170,共3页 Liaoning Journal of Traditional Chinese Medicine
关键词 甲状腺机能亢进 抗甲协定方 丙基硫氧嘧啶 中西医结合疗法 hyperthyroidism Kangjia Recipe propylthiouraeil integrative medicine therapy
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