摘要
Vogt-小柳-原田综合征是一种常见的疾病。我们对42篇文献(含1589例)进行分析整理,结果本病发病年龄8～76(平均36.03)岁。男835例,女736例。双眼同时或先后发病1585例,4例为单眼发病。发病时视力半数<0.2,也有少部分接近正常。眼外损害以头痛最常见,约为67%,耳鸣和脱发的发生率分别为39%和33%。也有相当部分患者并未出现任何眼外症状。眼底荧光血管造影是最重要检查,主要表现为斑驳状高荧光,视盘染色和多湖样视网膜下染料积存。所有患者均采用激素治疗,复发病例部分加用了免疫抑制。经过治疗,有超过3/4的患者视力保持在0.6以上,超过半数的患者可以获得1.0以上的视力。系统治疗的患者复发率较低。白内障和青光眼是本病的主要并发症,发生率为20%和9%。
Vogt-Koyanagi-Harada （VKH） syndrome is a common disease. 42 papers containing a total of 1 589 cases shown that obtained. Age of onset in patients with VKH syndrome varied from 8 to 76 （average age 36）. Male were 835, and female were 736. Patients whose binoculus involved in VKH syndrome at the same time or in succession were 1 585 and monocular incidence was in 4 cases. Headache was noted in 67% of these patients. Tinnitus and alopecia were noted in 39% and 33%. Before the treatment, patients of visual acuity 〈 0.2 were found to be 50%, and few was close to normal. Fundus fluorescein angiography （FFA） is the most important examination, its main performance were mottled hyper- fluorescence; optic disc dyeing and cystic fluorescein reservoir. Corticosteroid were used in all cases. Some cases added immune agents. After treatment. Visual acuity ≥0.6 were found in 76%, and ≥0.1 were more than 50%. Relapse incidence （RI） of systemic therapy was lower. Cataract and glaucoma were the main complications, and incidence rate was nearly 20% and 9%.
出处
《国际眼科杂志》
CAS
2009年第7期1401-1403,共3页
International Eye Science
