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上消化道重建术后肠腔菌群的改变 被引量:1

The alteration of intestinal flora in patients with reconstruction of the upper gastrointestinal tract
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摘要 目的:探讨上消化道重建术后空肠上段肠道菌群的种类、数量与感染并发症的关系。方法:前瞻性观察上消化道手术病人52例。分别于术中、术后第2天和第5天抽取病人空肠上段肠液,测定肠液菌群种类和菌落计数,同时检测病人血浆内毒素水平。结果:术中、术后第2和第5天无明显菌群失调及细菌移位发生(各菌种之间细菌菌落数比较,P>0.05)。术中、术后第2和第5天血浆内毒素水平无显著性差异(P>0.05)。结论:上消化道重建术后,无明显肠道菌群紊乱。 Objective : To investigate changes in species and amounts of intestinal flora after reconstruction of upper digestive tract, and the relationship with the infective complications. Methods: 52 patients with advanced malignancy being performed reconstruction of upper gastrointestinal tract was prospectively observed . The species of bacteria and counts of the colony forming units (CFU) were measured from juice taking from the upper jejunum through nasointestinal tube during operation, the second day and the fifth day after operation. Meanwhile, the plasma endotoxin concentration was determined with the modified chromogenic limulus assay. Results: There weren t significant changes of intestinal flora in species and amounts between groups ( P 〉0.05. ) No any signs of bacterial translocation were seen.There was no significant difference for the level of plasma endotoxin There is no disorder of intestinal flora and bacterial translocation during per digestive tract reconstruction successfully. between groups. the perioperative period after upper digestive tract reconstruction successfully.
出处 《肠外与肠内营养》 CAS 北大核心 2009年第4期228-230,共3页 Parenteral & Enteral Nutrition
关键词 肠道菌群 菌群紊乱 消化道重建 Intestinal flora Bacterial translocation Gastrointestinal tract
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