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肺癌的全基因组关联研究进展 被引量：1

Genome Wide Association Study on Lung Cancer
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摘要 肺癌是世界范围内最常见的癌症，属于多基因疾病，即多个基因的变异共同参与发病。研究表明携带基因变异的个体比非携带者具有更高的患病风险性，故将这些基因称为“易感基因”。吸烟是肺癌的主要危险因素，但吸烟人群中有80％以上的个体不会罹患肺癌，而非吸烟者中仍有10％-15％的肺癌患者，说明个体对肺癌的遗传易感性存在差异。
作者 牛晓敏 艾星浩 陆舜
机构地区 上海交通大学附属胸科医院
出处 《中国肺癌杂志》 CAS 2009年第7期792-798,共7页 Chinese Journal of Lung Cancer
关键词 肺癌患者 全基因组 基因变异 吸烟人群 多基因疾病 遗传易感性 世界范围 易感基因
分类号 R734.2 [医药卫生—肿瘤] R373.1 [医药卫生—病原生物学]
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参考文献30

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二级参考文献30

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中国肺癌杂志
2009年 第7期

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