摘要
目的:探讨甲基强的松龙(MP)联合中药益肾通痹汤在腰椎术后脊神经根损伤中的保护作用。方法:所选病例共44例,其中男性27例,女性17例;年龄在28岁～72岁,平均为47.77±11.25岁。根据术后具体用药的不同,随机分为MP组(A组),MP加中药益肾通痹汤组(B组)。在术后第1、7、15天及术后第1、3月分别用VAS和JOA评分进行疗效评估。结果:所有患者在术后2周内的VAS及JOA分值均明显优于术前;但A、B两组间比较差异无统计学意义(P>0.05)。术后3个月B组VAS分值和术后1月,3月的JOA评分均明显优于A组,且差异有统计学意义(P<0.05)。结论:MP对于腰椎术后脊神经根损伤,在短期内能改善神经根水肿症状,减少术后根性疼痛。与中药益肾通痹汤联合应用可显著提高腰椎手术后的长期疗效,有助于患者神经功能的恢复。
Objective： To explore the protective effect of Methylprednisolone （MP） combined with Chinese medicine Yishen Tongbi Decoction （YTD） on the lumbar nerve root injury after operation. Methods： A total of 44 cases were selected, including 27 males and 17 females, aging from 28 to 72 years, averagely （47.77 ± 11.25） years. According to the different postoperative specific medication, the eases were randomly divided into MP group （A） and MP combined with traditional Chinese medicine YTD group （B）. VAS and JOA scales were applied on the 1st, 7th, 15th days and the 1st and 3rd months after the operation for each case. Results： VAS and JOA scores 2 weeks after the operation showed better results for all patients after the operation than before the operation, but there was no significant difference between group A and group B （P0.05）. VASscores of group Bon the 3rd month andJOA score on the ]st and 3rd months after the operation were obviously higher than those in group A （P〈0.05）. Conclusion：MP can mitigate nerve root edema and reduce radicular pain induced by lumbar operation in a short term. MP combined with Chinese medicine Yishen Tongbi Decoction can significantly increase the long--term effecl of lumbar spine surgery and recovery of neurological function.
出处
《中国中医骨伤科杂志》
CAS
2009年第7期40-42,共3页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词
腰椎手术
神经根损伤
甲基强的松龙
中药
益肾通痹汤
Lumbar spine surgery
Nerve root injury
Methylprednisolone
Chinese medicine
Yishen Tongbi Decoction
