摘要
文中以丁二酸、丁二醇和苄氧羰基保护的天冬氨酸为原料,通过熔融聚合法合成了聚(丁二酸丁二醇-co-CBz-天冬氨酸丁二醇)共聚酯(P(BS-co-BCD)),然后以Pd(10%(质量分数,下同))/C为催化剂高压氢化脱去保护基团得到含有活性氨基活性点的生物可降解聚(丁二酸丁二醇-co-天冬氨酸丁二醇)共聚酯(P(BS-co-BD))。利用凝胶渗透色谱(GPC)、红外光谱(FT-IR)、核磁共振波谱(NMR)等研究了共聚物的结构和性能。测试表明共聚酯的水接触角比聚丁二酸丁二醇酯(PBS)低,表明加入含有氨基活性点的天冬氨酸链段提高了材料的亲水性。
Biomaterials with functional lateral groups have attracted considerable attention. A novel biodegradable aliphatic copolyester poly（butylene succinate-co-CBz- butylene aspartic acid） （P（BS-co-BCD）） has been synthesized through a condensation copolymerization based on N-Benzyloxycarbonyl（CBz）-L-aspartic acid, succinic acid and 1,4- butanediol. The copolymer P（BS-CO-BD） containing functional amino groups on the side chain, was achieved through consequently Pd/C catalyzed hydrogenation reaction. The resultant copolyester was characterized by gel permeation in chromatography （GPG）, fourier transform infrared spectroscopic（FT-IR） and nuclear magnetic resonance （NMR） spectrum. The water contact angles of the copolymers were lower than those of poly（butylene succinate） polyester （PBS）, which indicated that the hydrophilicity of copolymers have been greatly improved for the introducing of aspartic acid chains than that of PBS.
出处
《高分子材料科学与工程》
EI
CAS
CSCD
北大核心
2009年第7期125-128,共4页
Polymer Materials Science & Engineering
