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合成、自体及组织工程阴茎增粗充填材料的特性及其临床应用 被引量:3

Characteristics and clinical application of synthesized,autologous and tissue engineered penis thickening hydraulic filling materials
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摘要 不同种类阴茎增粗充填材料各有优缺点。天然生物组织材料为自身组织、取材方便、无毒性、无刺激性、组织相容性好、无排异反应,但有移植脂肪吸收、供区切口瘢痕、远期外形不佳等缺点。人工合成生物材料中硅橡胶假体可塑性强、不被机体代谢、吸收和降解等,但有异物感、易使皮肤破溃感染等缺点;膨体聚四氟乙烯组织相容性好、材质软、易塑形,但价格昂贵;聚丙烯酰胺水凝胶、聚甲基丙烯酸甲酯组织相容性好、不引起免疫反应、易于注射,但缺点是易形成硬结,若发生了并发症很难取出。组织工程材料是近年来阴茎增粗研究的重点,但其研究尚处在起步阶段,多数报道仅处于实验室阶段,在国内推广尚需时日。文章对有关阴茎增粗充填材料进行整理,分析不同种类充填材料在阴茎增粗术中的应用。 The different types of penis thickening hydraulic filling materials have the advantage and disadvantage. The natural biological tissue material for own organization is convenient, avirulent, nonirritant, with good histocompatibility, without rejection, but has the transplant fat absorption, margin scar at donor site, and poor long-term appearance. Synthesized biological material silica gel phantom presented strong plasticity, could not affect by organism metabolism, absorption and degeneration, but had shortcomings, such as the feeling of foreign body, and skin infection. Varicosity polytetrafluoroethylene presented good histocompatibility, soft material, easy to be shaping, but high cost. The polyacrylamide hydrogel and the polymethyl acrylic acid methyl ester presented good histocompatibility, could not cause the immune response, easy to inject, but the shortcoming was easy to form the induration, but if had the complication to be very difficult to take out. Tissue engineered material was presently the key point in penis thickening research, but its research still occupied the start stage. The most reports were only at the laboratory stage. It requires some times for domestic application. This study summarized the penis thickening hydraulic filling materials, and analyzed the application of various filling materials in penis thickening technique.
出处 《中国组织工程研究与临床康复》 CAS CSCD 北大核心 2009年第29期5751-5754,共4页 Journal of Clinical Rehabilitative Tissue Engineering Research
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