期刊文献+

儿童不明原因晕厥诊断的多中心研究 被引量:12

Diagnosis of unexplained syncope in children: a multi-center study
原文传递
导出
摘要 目的探讨直立倾斜试验(HUTT)对儿童不明原因晕厥的诊断价值。方法晕厥组为2002年1月至2008年4月在北京、湖南、湖北、上海四地晕厥门诊就诊或住院的379例不明原因晕厥患儿,其中男171例,女208例;年龄3-18岁,平均(12±3)岁。所有患儿通过常规检查仍不能明确患儿晕厥的原因时,进行基础直立倾斜试验(BHUTT)或舌下含化硝酸甘油激发的倾斜试验(SNHUTT)检查。对照组为10名身体健康、无晕厥及晕厥先兆病史的正常儿童,其中男5名,女5名;年龄9-15岁,平均(11.4±2.1)岁,其心血管、神经系统、心电图、超声心动图及X线胸片检查均正常;所有正常儿童均进行BHUTr或SNHUTT。结果在379例患儿中,286例患儿为自主神经介导性晕厥(75.5%)。晕厥患儿中67例为体位性心动过速综合征(17.7%);157例为血管迷走性晕厥血管抑制型(41.4%);14例为血管迷走性晕厥心脏抑制型(3.7%);47例为血管迷走性晕厥混合型(12.4%);1例患儿为直立性低血压(0.3%);93例患儿仍为不明原因晕厥(24.5%)。在晕厥组和对照组中,BHUTT的诊断阳性率分别为55.9%和0,SNHUTT的诊断阳性率分别为75.5%和20.0%。BHUTF阳性患者在BHUTF过程中出现阳性反应的时间平均为(16±12)min,阳性反应出现时的体位均为倾斜60°体位;SNHUTF阳性患儿在SNHUqT过程中出现阳性反应的时间平均为(6±4)min,阳性反应出现时的体位均为倾斜60°体位并舌下含化硝酸甘油。结论应用HUTT可较好地、客观地对儿童自主神经介导性晕厥进行诊断,SNHUTT具有较高的诊断阳性率,明显提高了BHUTT的诊断阳性率,且阳性反应时间明显低于BHUTT。 Objective To examine the diagnostic value of head-up tilt test in children with unexplained syncope (UPS). Methods A total of 379 children (171 males, 208 females) aged 3 -18 years, mean age( 12 ± 3 ) years with unexplained syncope from Beijing, Hunan, Hubei and Shanghai and undergoing baseline head-up tilt tests (BHUTT) or head-up tilt tests potentiated with nitroglycerine (SNHUTT) under a quiet circumstance were selected as the syncope group. Ten healthy children (5 males, 5 females) aged 9- 15 years with a mean age of (11.4 ± 2. 1 ) years,were recruited as the control group. SPSS 10. 0 software was used for data analysis. Results In 379 children with unexplained syncope, 67 (17.7%) were of postural orthostatic tachycardia syndrome (POTS), 157 (41.4%) of vasovagal syncope vasoinhibitory pattern, 14 (3.7%) of vasovagal syncope cardioinhibitory pattern, 47 (12. 4% ) of vasovagal syncope mixed pattern, 1 (0. 3% ) of orthostatic hypotension (OH) and 93 children (24. 5% ) of UPS. In syncope group and control group, the positive rate of BHUTT was 55.9% and 0 respectively and it was 75.5% and 20.0% respectively for SNHUTT. During BHUTT, the mean time of positive response occurrence was (16 ± 12) minutes, and the posture when positive response appeared was at a tilt angle of 60 degrees. For SNHUTT, the mean time of positive response occurrence was (6 ± 4) minutes and the posture was at a tilt angle of 60 degrees when potentiated with nitroglycerine. Conclusion HUTF is an objective diagnostic tool of UPS. With a high diagnostic positive rate of BHUTT. Meanwhile the time of positive response BHUTT. rate, SNHUTr can improve the diagnostic positive occurrence during SNHUTT is markedly shorter than
出处 《中华医学杂志》 CAS CSCD 北大核心 2009年第28期1947-1950,共4页 National Medical Journal of China
基金 长江学者奖励计划 首都医学发展基金(2007-2003)
关键词 倾斜台试验 晕厥 血管迷走神经性 儿童 Tilt-table test Syncope, vasovagal Child
  • 相关文献

参考文献6

二级参考文献35

  • 1胡大一.倾斜试验与血管神经性晕厥[J].心脏起搏与心电生理杂志,1994,8(3):161-162. 被引量:13
  • 2李雯,王成,李茗香,林萍,郑慧芬,谢振武.儿童血管迷走性晕厥的诱因与先兆分析[J].中国急救医学,2006,26(2):87-89. 被引量:14
  • 3杜军保,中华儿科杂志,1997年,35卷,309页
  • 4陈孟扬,中华心血管病杂志,1994年,22卷,227页
  • 5李宜富,中华心血管病杂志,1994年,22卷,181页
  • 6Low PA,Opfer-Gehrking TL, Textor SC, et al. Postural tachycardia syndrome (POTS). Neurology, 1995, 45:S19-S25.
  • 7Stewart JM. Orthostatic intolerance in pediatrics. J Pediatr, 2002,140:404-411.
  • 8Stewart JM, Weldon A. Inappropriate early hypotension in adolescent: a form of chronic orthostatic intolerance with defective dependent vasoconstriction. Pediatr Res, 2001,50:97-103.
  • 9田中英高.起立性調節障害[J].小児科診療,2001,64:160-160.
  • 10Blair P, Grubb M, Yousurf K, et al. The postural orthostatic tachycardia syndrome: current concepts in pathophysiology diagnosis and management. J Interv Card Electrophysiol, 2001,5:9-16.

共引文献193

同被引文献143

引证文献12

二级引证文献135

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部