期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

牛SCD基因研究进展 被引量：13

Advances in Bovine Stearoyl-Coenzyme A Desaturase(SCD) Gene
下载PDF
导出
摘要 硬脂酰辅酶A去饱和酶(SCD)是催化主要包括棕榈酰CoA(C16:0)、硬脂酰CoA(C18:0)在内的饱和脂肪酸(SFA)产生单不饱和脂肪酸(MUFA)合成的关键酶,对牛奶、脂肪组织中脂肪酸的组成以及肌肉间脂肪沉积有着重要影响。文章概述了近年来牛SCD基因相关的研究进展。 Stearoyl-coenzyme A desaturase （SCD） is the key enzyme that is responsible for the conversion of saturated fatty acids to monounsaturated fatty acids, with stearoyl-CoA （C18：0） and palmitoyl-CoA （C16：0） as its substrates. It is very important for the composition of milk, adipose tissues and deposition of fat in muscle. The progress of bovine SCD gene was reviewed in this paper.
作者 陶璇 张健 魏学良
机构地区 重庆市畜牧科学院 西南大学动物科技学院
出处 《中国草食动物》 2009年第4期57-59,共3页 China Herbivores
基金 重庆市重大科技专项(CSTC 2008AD1100)资助
关键词 牛 SCD △^9-去饱和酶 bovine SCD △9-desaturase
分类号 S827.2 [农业科学—畜牧学]
  • 相关文献

参考文献20

  • 1Mele M, Conte G, Castiglioni B, et al. Stearoyl-coenzyme A desaturase gent polymorphism and milk fatty acid composition in Italian Holsteins[J]. Journal of Dairy Science, 2007, 90(9): 4458-4465.
  • 2Ntambi J M, Buhrow S A, Kaestner K H, et al. Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl CoA desaturase[J]. Journal of Biological Chemistry, 1988, 263(33): 17291-17300.
  • 3Kaestner K H, Ntambi J M, Kelly T J,et al. Differentiation-induced gene expression in 3T3-L1 Preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase[J]. Journal of Biological Chemistry, 1989, 264(25): 14755-14761.
  • 4Zheng Y, Prouty S M, Harmon A,et al,Scd3 --a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin[J]. Genomics, 2001, 71(2): 182- 191.
  • 5Miyazaki M, Jacobson M J, Man W C,et al. Identification and characterization of routine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary faetors[J]. Journal of Biological Chemislry, 2003, 278(36): 33904-33911.
  • 6Zhang L, Ge L, Parimoo S,et al. Human stearoyl-CoA desaturase alternative transcripts generated from a single gene by usage of tan dem polyadenylation sites[J]. The Biochemical Journal, 1999, 340 255-264.
  • 7Wang J, Yu L, Schmidt R E,et al. Characterization of HSCD5, a novel human stearoyl- CoA desaturase unique to primates[J]. Biochemical and Biophysical Research Communications, 2005, 332(3): 735-742.
  • 8Campbell E M, Gallagher D S, Davis S K, et al. Rapid communica tion: mapping of the bovine stearoyl-CoA desaturase(SCD) gene to BTA26[J]. Journal of Animal Science, 2001, 79: 1945-1955.
  • 9Jiang Z, Michal J J, Tobey D J, et al. Significant associations of stearoyl-CoA desaturase (SCDI) gene with fat deposition and composition in skeletal muscle[J]. International Journal of Biological Sciences, 2008, 4(6): 345-351.
  • 10Lengi A J, Corl B A. Identification and characteration of a novel bovine stearoyl-CoA desaturase isoform with homology to human SCDS[J]. Lipids, 2007, 42(6):499-508.

二级参考文献10

  • 1Baumgard L H,Matitashvili E,Corl B A,et al.Trans-10,cis-12 conjugated linoleic acid decreases lipogenic rates and expression of genes involved in milk lipid synthesis in dairy cows.J Dairy Sci,2002,85:2155～2163.
  • 2Bu D P,Wang J Q,Dhiman T R,et al.Effectiveness of linoleic and linolenic acid for enhancing conjugated linoleic acid in milk from dairy cows.J Anim Sci,2006,84(1):64～65.
  • 3Corl B A,Baumgard L H,Dwyer D A,et al.The role of delta(9)-desaturase in the production of cis-9,trans-11 CLA.J Nutr Biochem,2001,12:622～ 630.
  • 4Corl B A,Barbano D M,Bauman D E,et al.Cis-9,trans-11 cla derived endogenously from trans-11 18:1 reduces cancer risk in rats.J Nutr,2003,133:2893～2900.
  • 5Griinari J M,Corl B A,Lacy S H,et al.Conjugated linoleic acid is synthesized endogenously in lactating dairy cows by deta-9 desaturase.J Nutr,2000,30:2285 ～ 2291.
  • 6Kinsella J E.Stearyl coa as a precursor of oleic acid and glycerolipids in mammary microsomes from lactating bovine:Possible regulatory step in milk triglyceride synthesis.Lipids 1972,7:349～355.
  • 7Ntambi J M.Dietary regulation of stearoyl-coa desaturase 1 gene expression in mouse liver.J Biol Chem,1992,267:10925 ～10930.
  • 8Piperova L S,Tete B Br,Bruckental I,et al.Mammary lipogenic enzyme activity,trans fatty acids and conjugated linoleic acids are altered in lactating dairy cows fed a milk fat -depressing diet.J Nutr,2000,130:2568～2574.
  • 9Sessler A M,Ntamb J M.Polyunsaturated fatty acid regulation of gene expression.J Nutr,1998,128:923～926.
  • 10Singh K,Hartley D G,McFadden T B,et al.Dietary fat regulates mammary stearoyl coA desaturase expression and activity in lactating mice.J Dairy Res,2004,71:1～ 6.

共引文献9

同被引文献145

引证文献13

二级引证文献27

中国草食动物
2009年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部