摘要
目的:探讨左氧氟沙星不良反应(ADR)的临床特点。方法:对2006年1月至2008年1月间我院门诊及住院患者中出现左氧氟沙星ADR患者70例进行研究,总结分析ADR发生的相关因素、临床表现类型以及治疗和预后。结果:本组年龄<60岁患者有25例(35.71%),年龄≥60岁患者有45例(64.29%);静脉用药发生ADR患者64例(91.43%),口服用药者6例(8.57%);联合用药致ADR 52例(74.29%),单独用药18例(25.71%)。本组皮肤反应25例(35.71%),发生率位居首位;其次为消化系统15例(21.43%),全身性损害12例(17.14%)等。所有患者经调整滴速、停药或对症处理后症状均消失。结论:左氧氟沙星ADR发生率日趋升高,临床医护应积极掌握其相关因素、临床表现以及处理措施,以减少ADR的发生。
Objective： To investigate the clinical feature of adverse reactions （ADR ） on levofloxacin. Method ： The datas of 70 cases with adverse reaction of levofloxacin in our hospital from January in 2006 to January in 2008 were analysed to summarize the correlation factors of ADR, clinical manifestations, treatment and prognosis. Result： There were 25 cases （ 35.71% ） who were more than 60 years old and 45 cases （64.29%）who were less than 60 years old. There were 64 cases （91.43% ） with adverse reaction by vein injection and 6 cases （8.57% ） with adverse reaction by mouth. There were 52 cases （72.49% ） with drug combination and 18 cases （ 25.71% ） with single drug . The rate of cutaneous reaction was highest in the justing droping, discontinuation and so on. Conclusion： The rate of ADR about levofloxacin is increasing quickly, so the clinic doctors and nurses must grasp the correlation factor of ADR, clinical manifestations and treatment to decrease the rate of ADR.
出处
《河北医学》
CAS
2009年第9期1075-1078,共4页
Hebei Medicine
