摘要
目的了解近3年来广州地区儿童肠道轮状病毒感染情况。方法收集2005年1月至2007年12月收治的包括门诊和住院的急性腹泻患儿的大便标本,采用免疫胶体金技术对标本进行轮状病毒抗原检测。结果轮状病毒2005、2006和2007年平均感染率分别为44.70%、38.22%和39.99%;与2006、2007年相比,2005年轮状病毒感染高峰和波谷均向后推延1个月。抗原检测阳性例数在6～24个月婴幼儿最高,全年感染率在性别上差异无统计学意义。结论轮状病毒是引起婴幼儿病毒感染性腹泻的主要病原体,气候可能对广州地区轮状病毒感染有较大影响。
Objective To study the occurrence of rotavirus infection among children in Guangzhou area. Methods Stool specimens were collected from over 30,000 inpatients and outpatients, with an age of less than 5 years old, suffering from acute diarrhea admitted in Guangzhou Children＇s hospital during the period of Jan 2005 to Dec 2007. Immune colloidal gold technique was used to test the presence of rotavirus antigens in stool specimens. Results A total of 33,211 specimens were tested. The average positive rate of infection in 2005, 2006 and 2007 was 44.70%, 38.22% and 39.99%, respectively. Compared with 2006 and 2007, the peak of infection was one month delayed in 2005. The rate of positive rotavirus antigen detection was highest in infants aged 6-24 months. Sex difference in infection was not significant （P〉0.05）. Conclusion Rotavirus is the single most important causative agent of severe acute diarrhea among young children in Guangzhou, China. Climatological factors, such as temperature, may affect the epidemiologic patterns of rotavirus infection in Guangzhou.
出处
《热带医学杂志》
CAS
2009年第7期757-759,共3页
Journal of Tropical Medicine
关键词
腹泻
轮状病毒
抗原检测
diarrhea
rotavirus
antigen detection
