期刊文献+

甲状腺癌局部切除术后再手术的探讨 被引量:1

Reoperation after Local Resection of Thyroid Cancer
下载PDF
导出
摘要 目的:研究甲状腺癌行肿瘤切除或腺叶次全切除术后腺体残癌率和颈部淋巴结转移的情况,明确甲状腺癌的切除范围与手术方式。方法:对1996年~2005年间在外院行腺叶肿交瘤切除或次全切除术后来我院行二次手术治疗的57例甲状腺癌患者进行分析研究。结果:总的癌残留率为49.1%(28/57)。原发部位残癌率为29.8%(17,57),术后病理淋巴结转移癌21例,淋巴结转移率为52.5%(21/40),患侧颈部Ⅵ区淋巴结转移率为35.0%(14/40)。我院二次手术所致喉返神经麻痹的发生率为1.8%(1/57)。甲状腺癌颈淋巴结转移与被膜侵犯正相关。结论:甲状腺癌行肿块切除或腺叶次全切除术的术后残癌率较高。有被膜侵犯的甲状腺乳头状癌患者,应行改良性颈清扫术。术中疑为甲状腺癌时,应常规行颈部Ⅵ区探查,必要时应行该区清扫术。术中避免喉返神经和甲状旁腺的损伤。 Objective: To evaluate the rate of residual disease in the thyroid gland and that of cervical lymph node metastasis after preliminary local resection of thyroid cancer. Methods: From 1996 to 2005, a total of 57 thyroid cancer patients previously treated with nodulectomy or subtotal Iobectomy received reoperation. Results: The rate of residual disease at the primary site was 29.8 (17/57). The rate of lymphnode metastasis was 52.5% (21/40). The lymph node metastasis rate at level VI was 35.0 (14/40). The rate of laryngeal recurrent nerve injury was 1.8% (1/57) at the second operation. The cervical lymph node mteastasis was positively correlated with the capsule aggression. Conclusion: Because of high rate of local residual disease, nodulectomy or subtotal lobectomy alone is not indicated for thyroid cancer. Modified cervival lymphadenectomy is necessary for papillary thyroid carcinoma with capsule aggression. The exploration to level VI is needed for thyroid cancer. Parathyroid injury and laryngeal recurrent nerve injury should be avoided during surgery for thyroid carcinoma.
出处 《中国肿瘤临床》 CAS CSCD 北大核心 2009年第14期801-803,共3页 Chinese Journal of Clinical Oncology
关键词 甲状腺肿瘤 甲状腺切除术 改良性颈清扫术 再手术 Thyroid neoplasm Thyroidectomy Modified cervical lymphadenectomy Reoperation
  • 相关文献

参考文献10

二级参考文献50

  • 1朱永学,王弘士,吴毅,嵇庆海,黄彩萍.甲状腺乳头状癌Ⅵ区淋巴结的归属[J].中华外科杂志,2004,42(14):867-869. 被引量:112
  • 2杜宪武,邵俊荣,赵淑梅.复发性甲状腺癌37例临床分析[J].河南外科学杂志,2006,12(3):7-8. 被引量:2
  • 3邱杰,赵舒薇,张文伟,英信江,叶青,王海青,王宝东,孙爱华.甲状腺癌再次手术的临床分析[J].中国耳鼻咽喉颅底外科杂志,2006,12(2):113-115. 被引量:7
  • 4[4]HundahlSA, CadyB, Cunningham MP, et al.Initial results from a prospective cohort study of 5583 cases of thyroid carcinoma treated in the united states during 1996.U.S.and German Thyroid Cancer Study Group.An American College of Surgeons Commission on Cancer Patient Care Evaluation Study. Cancer,2000, 89:202-217.
  • 5[5]Vitale G, Caraglia M, Ciccarelli A.Current approaches and perspectives in the therapy of medullary thyroid carcinoma.Cancer, 2001, 91:1797-1808.
  • 6[6]Cady B, Presidential address:beyond risk groups-a new look at differentiated thyroid cancer. Surgery, 1998, 124:947-957.
  • 7Larijani B, Shirzad M, Mohagheghi MA, et al. Epidemiologic analysis of the Tehran Cancer Institute Data System Registry(TCIDSR)[J]. Asian Pac J Cancer Prev, 2004, 5(1):36-39.
  • 8Loh KG, Greenspan FS, Gee L, et al. Pathological tumor-nodemetastasis (pTNM) staging for papillary and follicular thyroid carcinomas: a retrospective analysis of 700 patients[J].J Glin Endocrinol Metab, 1997, 82(11):3553-3562.
  • 9Zhumadiiov Z, Gusev BI, Takada J, et al. Thyroid abnormality trend over time in northeastern regions of Kazakstan, adjacent to the Semipalatinsk nuclear test site: a case review of pathological findings for 7271 patients[J].J Radiat Res, 2000, 41 (1):35-44.
  • 10Ferlay J, Bray F, Pisani P, et al. GLOBOCAN 2000. Cancer Incidence, Mortality and Prevalence Worldwide [M]. IARC press Lyon, 2001.

共引文献199

同被引文献20

  • 1刘经祖.分化型甲状腺癌外科手术方式[J].中国实用外科杂志,2004,24(10):579-581. 被引量:47
  • 2黄志强.从微创技术到微创观念——今日外科与明日外科[J].中国微创外科杂志,2007,7(1):1-1. 被引量:58
  • 3刘跃武,李小毅,刘洪讽,高维生,赵玉沛.分化型甲状腺癌选择性颈淋巴结清除术的临床应用[J].中华外科杂志,2007,45(13):868-870. 被引量:16
  • 4Davies L,Welch HG. Increasing incidence of thyroid cancer in the United States, 1973-2002 [ J ]. JAMA,2006,295 ( 18 ) :2164-2167.
  • 5Mazzaferri EL, Kloos RT. Clinical review 128:Current approaches to primarpy for papillary and follicular thyroid cancer [ J ]. J Clin Endocrinol Metab ,2001,86 ( 4 ) : 1447-1463.
  • 6Sakorafas GH, Giotakis J, Stafyla V. Papillary thyroid microcarci- noma: a surgical perspective [ J ]. Cancer Treat Bey, 2005,31 ( 6 ) : 423438.
  • 7Ito Y, Miyauehi A, Inoue H, et al. An observational trial for papilla- ry thyroid mierecarcinoma in Japanese patients[ J ]. World J Surg,2010,34:28-35.
  • 8Lundgren CI, Hall P, Dickrnan PW, et al. Influence of surgical and postoperative treatment on smvival in differentiated thyroid cancer [J].Br J Surg,2007,94(5) :571-577.
  • 9Sywak M, Comford L, Roach P, et al. Routine ipsilateral level VI lymphadenectomy reduces postoperative thyroglobulin levels in papillary thyroid cancer [ J ]. Surgery, 2006, 140 6 ) : 1000-1005.
  • 10Moo TA,McGill J, Allendorf J, et al. Impact of prophylactic cen- tral neck lymph node dissection on early recurrence in papillary thyroid carcinoma[ J ]. World J Surg,2010,34 : 1187-1191.

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部