摘要
目的:探讨康莱特(KLT)腔内注射对恶性胸腔积液治疗的价值。方法:观察27例恶性胸腔积液患者腔内注射KLT后的疗效、不良反应及外周血免疫指标变化。结果:KLT腔内注射的有效率77.7%,不良反应为发热和胸痛,分别占11.1%与3.7%。59.2%患者KPS评分增高。中位缓解4.6个月,中位生存期7个月。结论:KLT腔内注射对恶性胸腔积液有效,不良反应少,适用于老年体弱经、全身情况较差的恶性胸腔积液患者胸腔内局部治疗。
Objective： To study the efficacy of KLT by intrapleural injection in treating malignant pleural effusion. Methods： To observe the responses, adverse reactions and peripheral blood immune indexes in 27 cases with malignant pleural effusion after the intrapleural injection of KLT. Results： The response rate was 77.7% , adverse reactions included fever（ 11.1% ） and chest pain（ 3.7% ）. KPS points for 59.2% patients were elevated, the median remission time was 4.6 months and the median survival time was 7 months. Conclusion： KLT（ intrapleural injection） has a good effect in treating malignant pleural effusion,with less adverse reactions.
出处
《现代肿瘤医学》
CAS
2009年第8期1497-1498,共2页
Journal of Modern Oncology
关键词
康莱特
恶性胸腔积液
腔内注射
KLT
malignant pleural effusion
intrapleural injection
